Evidence map›Paper›PMID 36352896›Full record

ReviewJHEP reports : innovation in hepatology2022

What to do about hepatocellular carcinoma: Recommendations for health authorities from the International Liver Cancer Association.

Manon Allaire, Jordi Bruix, Marko Korenjak, Sarah Manes, Zorana Maravic, Helen Reeves, Riad Salem, Bruno Sangro, Morris Sherman

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in JHEP reports : innovation in hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. International perspectives on LI-RADS.Abdominal radiology (New York) · 2025
    Review
  9. Review
  10. Article
  11. Evolving epidemiology of HCC in Spain.JHEP reports : innovation in hepatology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. New insights into mechanisms and interventions of locoregional therapies for hepatocellular carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 6 countries.

Manon AllaireAP-HP Sorbonne Université, Hôpital Universitaire Pitié-Salpêtrière, Service d'Hépato-gastroentérologie, Paris, France.
Jordi BruixUniversity Hospital Clinic IDIBAPS, Barcelona, Spain.
Marko KorenjakEuropean Liver Patients' Association (ELPA), Brussels, Belgium.
Sarah ManesGlobal Liver Institute Washington District of Columbia, USA.
Zorana MaravicDigestive Cancers Europe, Brussels, Belgium.
Helen ReevesThe Newcastle University Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK.
Riad SalemDepartment of Radiology, Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Chicago, IL 60611, USA.
Bruno SangroLiver Unit and HPB Oncology Area, Clinica Universidad de Navarra and CIBEREHD, Pamplona, Spain.
Morris ShermanUniversity Health Network, Toronto, Ontario, Canada.
Centro de Investigación Biomédica en Red · ESEuropean Federation of Allergy and Airways Diseases Patients Associations · BEEuropean Organisation for Research and Treatment of Cancer · BEHospital Clínic de Barcelona · ESLiver Institute Northwest · USNewcastle University · GBNorthwestern Memorial Hospital · USUniversité Paris Cité · FRUniversity Health Network · CA

Funding

Cancer Research UK 26813
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a major public health problem worldwide for which the incidence and mortality are similar, pointing to the lack of effective treatment options. Knowing the different issues involved in the management of HCC, from risk factors to screening and management, is essential to improve the prognosis and quality of life of affected individuals. This document summarises the current state of knowledge and the unmet needs for all the different stakeholders in the care of liver cancer, meaning patients, relatives, physicians, regulatory agencies and health authorities so that optimal care can be delivered to patients. The document was commissioned by the International Liver Cancer Association and was reviewed by senior members, including two ex-presidents of the Association. This document lays out the recommended approaches to the societal management of HCC based on the economic status of a given region.

Indexed as

AASLD, American Association for the Study of Liver DiseaseAFP, alpha-fetoproteinAlcohol consumptionALT, alanine aminotransferaseAPRI, aspartate aminotransferase-to-platelet ratio indexBCLC, Barcelona clinic liver cancercTACE, conventional TACEDCP, des-gammacarboxy prothrombinDEB-TACE, TACE with drug-eluting beadsEASL, European Association for the study of the LiverEBRT, external beam radiation therapyELF, enhanced liver fibrosisGGT, gamma-glutamyltransferaseHCC, hepatocellular carcinomaHepatocellular carcinomaHepatocellular carcinoma surveillanceHepatocellular carcinoma treatmentLi-RADS, Liver Imaging Reporting and Data SystemNAFLD, non-alcoholic fatty liver diseaseObesityRFA, radiofrequency ablationTACE, transarterial chemoembolisationTARE, transarterial radioembolisationTKI, tyrosine kinase inhibitorViral hepatitis

Identifiers

PMID36352896
PMCPMC9638834
OpenAlexW4295007474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.