Evidence map›Paper›PMID 36352782›Full record

SynthesisJournal of cardiac surgery2022

Comparative effectiveness and safety of open triple-branched stent graft technique with stented elephant trunk implantation in treating Stanford type A aortic dissection: A trial sequential meta-analysis.

Lelin Bin, Jianbin Fei, Long Zhao, Ruofeng Hong, Wenyu Yang

Open access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lelin BinCardiovascular Surgery Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.
Jianbin FeiCardiovascular Surgery Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.
Long ZhaoCardiovascular Surgery Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.
Ruofeng HongCardiovascular Surgery Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.
Wenyu YangCardiovascular Surgery Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China.ORCID http://orcid.org/0000-0003-4051-8894
Ningbo No. 2 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal surgical intervention for Stanford type A aortic dissection is controversial. The aim of this trial sequential meta-analysis was to investigate the comparative effectiveness and safety of open triple-branched stent graft and stent elephant trunk implantation for total aortic arch reconstruction in Sandford type A aortic dissection.

methodsPubMed, Embase, Cochrane library, Chinese Biomedical Literature database (CBM), and China National Knowledge Infrastructure (CNKI) were searched for retrieving relevant studies from inception to February 28, 2022. We evaluated 30-day mortality, procedure-related time including cardiopulmonary bypass (CPB), aortic cross-clamp (ACC), and selective cerebral perfusion (SCP), the incidence of postoperative complications including paralysis, cerebral embolism, and acute renal failure, intensive care unit (ICU) time, and medical expenditure. Statistical analysis was performed by RevMan 5.4 and trial sequential analysis (TSA) software.

resultsSix studies involving 260 dissection cases were included eventually. Total aortic arch reconstruction with open triple-branched stent graft was comparable to the stented elephant trunk implantation in 30-day mortality, incidence of postoperative complications, ICU time, and medical expenditure, but open triple-branched stent graft was related to shorter procedure-related time including CPB (mean difference [MD] = -46.11, 95% confidence interval [CI] = -67.24 to -24.98, p < .001), ACC (MD = -42.82, 95% CI = -66.74 to -18.90, p < .001), and SCP (MD = -17.88, 95% CI = -33.36 to -2.39, p = .02). TSA confirmed robustness of findings.

conclusionsOur analysis suggested that total aortic arch reconstruction with open triple-branched stent graft may be an effective and simplified procedure than the stented elephant trunk implantation.

Indexed as

Aortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationAorta, ThoracicBlood Vessel ProsthesisHumansPostoperative ComplicationsRetrospective StudiesStentsTreatment Outcomeaortic dissectionmeta-analysisStanford classificationtriple-branched stenttype A

Identifiers

PMID36352782
PMCPMC10100206
OpenAlexW4308682685

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.