ArticleEuropean journal of medical research2022
The association between the body height and cardiovascular diseases: a retrospective analysis of 657,310 outpatients in Germany.
Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 14 citations in OpenAlex.
- Gestational exposure to organophosphate ester flame retardants and child growth in weight, height, and body mass index at age 2-10 years: the Environmental influences on Child Health Outcomes Program.Environmental research · 2026Article
- Non-genetic component of height as a surrogate marker for childhood socioeconomic position and its association with cardiovascular and brain health: results from HCHS/SOL.medRxiv : the preprint server for health sciences · 2026Article
- Real-World Cardiovascular Research Using the German IQVIA Disease Analyzer Database: Methods, Evidence, and Limitations (2000-2025).Journal of cardiovascular development and disease · 2026Review
- The Association Between Height-Related Novel Anthropometric Indices and Cardiovascular Events: A Cross-Sectional Insight From the MASHAD Cohort Study.Health science reports · 2026Article
- Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner.BMC medicine · 2025Article
- Risk prediction of cardiovascular events in peritoneal dialysis patients.BMC nephrology · 2025Article
- TEMR: Trans-ethnic mendelian randomization method using large-scale GWAS summary datasets.American journal of human genetics · 2025Article
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Authors and funding
7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease (CVD) represents the leading cause of death worldwide. The identification of individuals at increased risk of CVD is essential to reduce its morbidity and mortality globally. Based on existing data on a potential association between the individual body height and the risk for CVD, we investigated this association in a large cohort of outpatients in Germany.
methodsA total of 657,310 adult outpatients with available body height data from the Disease Analyzer (IQVIA) database were included in Germany between 2019 and 2021. The prevalence of common CVD diagnoses (hypertension, coronary heart disease, atrial fibrillation and flutter, heart failure, ischemic stroke, and venous thromboembolism) was evaluated as a function of the patients' body height stratified by age and sex.
resultsIn both sexes, the prevalence of hypertension, coronary heart disease, heart failure, and ischemic stroke was higher among patients of smaller body height. In contrast, the prevalence of atrial fibrillation and venous thromboembolism was higher in taller patients. In age- and BMI-adjusted logistic regression analyses, an increased body height was negatively associated with coronary heart disease (OR = 0.91 in women and OR = 0.87 in men per 10-cm increase in height) and strongly positively associated with atrial fibrillation (OR = 1.25 in women and men) and venous thromboembolism (OR = 1.23 in women and OR = 1.24 in men).
conclusionWe present the first data from a large cohort of outpatients in Germany providing strong evidence for an association between the body height and common CVD. These data should stimulate a discussion as to how far the body height should be implemented as a parameter in stratification tools to assess CVD risk in order to further reduce cardiovascular morbidity and mortality in the future.
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