ArticleBMC pulmonary medicine2022
Long-term dyspnea, regional ventilation distribution and peripheral lung function in COVID-19 survivors: a 1 year follow up study.
Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04343053 (Patterns and Changes in Platelet Reactivity, Thrombotic Status and Endothelial Function in Hospitalized Patients with SARS-Cov-2 Infection), which is not on this map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Patterns and Changes in Platelet Reactivity, Thrombotic Status and Endothelial Function in Hospitalized Patients with SARS-Cov-2 Infection
Who cites it
27 citing papers in PubMed, 34 citations in OpenAlex.
- Evaluation of long-term sequelae by cardiopulmonary exercise testing 12 months after hospitalization for severe COVID-19.BMC pulmonary medicine · 2023Trial
- Distribution of pulmonary ventilation in women with post-COVID-19 before and after the use of a respiratory incentive device (UBICU): a pilot study.Frontiers in digital health · 2026Article
- Innovation in technologies for monitoring lung function in patients with respiratory disease.Breathe (Sheffield, England) · 2025Article
- The post-COVID-19 pulmonary sequelae: manifestations, mechanisms and treatment strategies.Journal of thoracic disease · 2025Review
- Electrical impedance tomography: from technical innovations to bedside clinical solutions.World journal of emergency medicine · 2025Article
- Quantitative Characterization of Respiratory Patterns on Dynamic Higher Temporal Resolution MRI to Stratify Postacute Covid-19 Patients by Cardiopulmonary Symptom Burden.Journal of magnetic resonance imaging : JMRI · 2024Article
- Musculoskeletal, Pulmonary, and Cardiovascular COVID-19 Sequelae in the Context of Firefighter Occupational Health: A Narrative Review.International journal of environmental research and public health · 2024Review
- Correlating COVID-19 severity with biomarker profiles and patient prognosis.Scientific reports · 2024Article
- A proposed approach to pulmonary long COVID: a viewpoint.The European respiratory journal · 2024Article
- A follow-up study on respiratory outcomes, quality of life and performance perception of SARS-CoV-2 primary and reinfection in elite athletes: A 9-month prospective study.European journal of sport science · 2024Article
- Factors associated with phenotypes of dyspnea in post-COVID-19 condition: a cross-sectional study.Scientific reports · 2024Article
- Long COVID syndrome: An unfolding enigma.The Indian journal of medical research · 2024Review
- Association of MUC5B promoter polymorphism with interstitial lung changes after COVID-19: A preliminary observation.The Indian journal of medical research · 2024Article
- Two-year cardio-pulmonary follow-up after severe COVID-19: a prospective study.Internal and emergency medicine · 2024Observational
- Healthcare utilization 9 months pre- and post- COVID-19 hospitalization among patients discharged alive.PloS one · 2024Article
- Observational
- Visualizing exertional dyspnea in a post-COVID patient using electrical impedance tomography.Infection · 2023Article
- An ultra-small integrated COiScience · 2023Article
- Clinical Applicability of Electrical Impedance Tomography in Patient-Tailored Ventilation: A Narrative Review.Tomography (Ann Arbor, Mich.) · 2023Review
- The long-term impact of COVID-19 pneumonia on pulmonary function and exercise capacity.Journal of thoracic disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyspnea is common after COVID-19 pneumonia and can be characterized by a defective CO
methodsWe followed up at 1-year patients previously admitted to the respiratory units (intensive care or sub-intensive care unit) for COVID-19 acute respiratory failure at 1-year after hospital discharge. PFT (spirometry, DLCO), impulse oscillometry (IOS), measurements of the exhaled nitric oxide (FENO) and Electrical Impedance Tomography (EIT) were used to evaluate lung volumes, CO
resultsSixty-seven patients were admitted between October and December 2020. Of them, 42/67 (63%) patients were discharged alive and 33 were evaluated during the follow up. Their mean age was 64 ± 11 years and 24/33 (73%) were males. Their maximum respiratory support was in 7/33 (21%) oxygen, in 4/33 (12%) HFNC, in 14/33 (42%) NIV/CPAP and in 8/33 (24%) invasive mechanical ventilation. During the clinical examination, 15/33 (45%) reported dyspnea. When comparing the two groups, no significant differences were found in PFT, in the peripheral airway inflammation (FENO) or mechanical properties (IOS). However, EIT showed a significantly higher regional inhomogeneity in patients with dyspnea both during resting breathing (0.98[0.96-1] vs 1.1[1-1.1], p = 0.012) and during forced expiration (0.96[0.94-1] vs 1 [0.98-1.1], p = 0.045).
conclusionsNew onset dyspnea characterizes 45% of patients 1 year after COVID-19 pneumonia. In these patients, despite pulmonary function test may be normal, EIT shows a higher regional inhomogeneity both during quiet and forced breathing which may contribute to dyspnea. CLINICAL
trial registrationClinicaltrials.gov NCT04343053, registration date 13/04/2020.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.