ArticleAntimicrobial resistance and infection control2022
Lower risk of bloodstream infections for peripherally inserted central catheters compared to central venous catheters in critically ill patients.
Article in Antimicrobial resistance and infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Risk prediction models for central venous catheter-related complications in children: a systematic review.BMC pediatrics · 2026Pooled it
- Comparative safety and effectiveness of midline catheters vs. peripherally inserted central catheters: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Systematic review of ultrasound-guided central venous catheter placement-related complications in neonates and infants aged <12 months.The Journal of international medical research · 2024Pooled it
- Parenteral nutrition and hospital outcomes in Australian adults: A descriptive cohort study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Article
- Impact of a Multimodal Infection Control Intervention on Central Line-Associated Bloodstream Infections in the ICU.Antibiotics (Basel, Switzerland) · 2026Article
- A machine learning model for the early prediction of Gram-negative bloodstream infection in ICU patients.BMC medical informatics and decision making · 2026Article
- Topology preserving embedded network for PICC segmentation in pediatric X ray images.NPJ digital medicine · 2026Article
- A single-center study on epidemiology, microbial distribution, and mortality predictors in catheter-related bloodstream infections.BMC infectious diseases · 2025Article
- Efficacy of single-lumen and double-lumen peripherally inserted central catheters in patients undergoing digestive surgery within bundled care contexts.World journal of gastrointestinal surgery · 2025Article
- Development and validation of a nomogram risk prediction model for PICC-related thrombosis in children with hematological malignancies.Clinical and experimental medicine · 2025Article
- Trends in the epidemiology of intravascular device-associated bacteremia among French hematology patients: insights from the SPIADI prospective multicenter study, 2020-2024.Annals of hematology · 2025Article
- Reusable Tourniquets as Potential Transmitters of Infection: A Microbiological Analysis.Microorganisms · 2025Article
- Device associated healthcare associated infection (DA-HAI): a detailed analysis of risk factors and outcomes in a university hospital in Rome, Italy.Infection prevention in practice · 2024Article
- Differences in the Dwell Time of Peripherally Inserted Central Catheters between Patients with Catheter Colonization and Those Developing Central Line-Associated Bloodstream Infection: A Single Centre Retrospective Cohort Study.Antibiotics (Basel, Switzerland) · 2024Article
- Clinical characteristics and risk factors for right-sided infective endocarditis in Korea: a 12-year retrospective cohort study.Scientific reports · 2024Article
- Catheter-related thrombosis in stem cell recipients: comparison of different types of catheter.Haematologica · 2024Article
- A review on antimicrobial strategies in mitigating biofilm-associated infections on medical implants.Current research in microbial sciences · 2024Review
- User Perceptions of Avatar-Based Patient Monitoring for Intensive Care Units: An International Exploratory Sequential Mixed-Methods Study.Diagnostics (Basel, Switzerland) · 2023Article
- Healthcare Equipment and Personnel Reservoirs of Carbapenem-ResistantMicroorganisms · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeripherally inserted central venous catheters (PICCs) serve as an alternative to short-term central venous catheters (CVCs) for providing intravenous access in hospitalized patients. Although a number of studies suggest that PICCs are associated with a lower risk of central line-associated bloodstream infections (CLABSIs) than CVCs, recent data concerning specific patient groups support the contrary. In this regard, we are comparing CVC- and PICC-related CLABSI rates developed in a selected group of critically ill inpatients and evaluating the CLABSI microbiological distribution.
methodsThe study was conducted at a tertiary care hospital in Greece between May 2017 and May 2019. We performed a two-year retrospective analysis of the data collected from medical records of consecutive adult patients who underwent PICC or CVC placement.
resultsA total of 1187 CVCs placed for 9774 catheter-days and 639 PICCs placed for 11,110 catheter-days, were reported and analyzed during the study period. Among CVCs, a total of 59 (4.9%) CLABSIs were identified, while among PICCs, 18 (2.8%) cases presented CLABSI (p = 0.029). The CLABSI incidence rate per 1,000 catheter-days was 6.03 for CVC group and 1.62 for PICC group (p < 0.001). The CLABSI rate due to multidrug-resistant organisms (MDROs) among the two groups was 3.17 in CVC group and 0.36 in PICC group (p < 0.001). Within CLABSI-CVC group, the most common microorganism detected was MDR Acinetobacter baumannii (27.1%) followed by MDR Klebsiella pneumoniae (22%). In CLABSI-PICC group, the predominant microorganism was Candida spp. (33.3%) followed by non-MDR gram-negative pathogens (22.2%).
conclusionsPICC lines were associated with significantly lower CLABSI rates comparing to CVC although they were in place longer than CVC lines. Given their longer time to the development of infection, PICCs may be a safer alternative for prolonged inpatient IV access. The high prevalence of CLABSI-MDROs depicts the local microbial ecology, emphasizing the need of public health awareness.
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