Evidence map›Paper›PMID 36352337›Full record

ArticleEndocrine2023

Metabolic effects of dopamine-agonists treatment among patients with prolactinomas.

Maryam Kabootari, Habibeh Shirmohammadli, Fatemeh Golgiri, Seyedarad Mosalamiaghili, Alireza Khajavi, Hamideh Akbari

Abstract read
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In one paragraph

Article in Endocrine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Maryam KabootariMetabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Habibeh ShirmohammadliClinical Research Development Unit, Sayad Shirazi Hospital, Golestan University of Medical Science, Gorgan, Iran.
Fatemeh GolgiriEndocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.
Seyedarad MosalamiaghiliStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Alireza KhajaviFaculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hamideh AkbariClinical Research Development Unit, Sayad Shirazi Hospital, Golestan University of Medical Science, Gorgan, Iran. dr.akbari.h@gmail.com.
Golestan University · IRIran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effect of cabergoline treatment on metabolic parameters including the Triglyceride-glucose (TyG) index in newly diagnosed patients with prolactinoma.

methods71 consecutive nondiabetic patients with prolactinoma were enrolled. Anthropometric and laboratory tests including TyG index were measured at baseline, 3 and 6 months visits. Treatment with cabergoline at the dose of 0.25 mg twice weekly was started and increased according to prolactin levels and continued for 6 months.

resultsAt the baseline examination, the mean (SD) age, body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) of patients were 36.2 (10.5) years, 29.2 (5.0) kg/m

conclusionShort-term treatment with cabergoline can significantly improve cardiovascular risk factors except for blood pressure. Moreover, the TyG index as a surrogate marker of insulin resistance decreased significantly after the reduction of prolactin by treatment. Generally, results were similar among both genders.

Indexed as

Pituitary NeoplasmsProlactinomaAdultBlood GlucoseBody Mass IndexCabergolineCholesterol, HDLDopamineDopamine AgonistsFemaleHumansMaleMiddle AgedProlactinRisk FactorsTriglyceridesBlood GlucoseCabergolineCholesterol, HDLDopamineDopamine AgonistsProlactinTriglyceridesCabergolineMetabolic syndromeProlactinomaTriglyceride-glucose (TyG) index

Identifiers

PMID36352337
OpenAlexW4308678880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.