Evidence map›Paper›PMID 36352322›Full record

ArticleInfection2023

Long-term follow-up after introduction of a systematic sexually transmitted infection screening program for men having sex with men living with HIV in a primary care setting: uptake, STI incidence, and risk factors for infection and reinfection.

Philipp J G Mathé, Susanne Usadel, Siegbert Rieg, Winfried V Kern, Matthias C Müller

Registry-linked trialAbstract read
In one paragraph

Article in Infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02149004 (Translational Research Platform of the TTU HIV of the German Center for Infection Research), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02149004 recruitingnot on this map

Translational Research Platform of the TTU HIV of the German Center for Infection Research (DZIF)

TypeobservationalSponsorUniversity Hospital of CologneRan2015 to 2035Enrolled10,000ConditionsHIV
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philipp J G MathéDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0448-5338
Susanne UsadelDepartment of Infection Medicine, Medical Service Centre Clotten, Freiburg, Germany.
Siegbert RiegDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.ORCID http://orcid.org/0000-0001-7493-7080
Winfried V KernDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2550-358X
Matthias C MüllerDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany. matthias.mueller@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0001-6952-8442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnnual screening for asymptomatic infections with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) is recommended by international guidelines in people living with HIV but uptake in routine care remains poor. This study analyzed the effects of the implementation of a CT/NG screening program in a primary HIV treatment center.

methodsIn this single-center cohort study, we included men having sex with men (MSM) living with HIV during the study period from January 2016 to December 2019. From January 2018 on, annual sexual health counseling including CT/NG screening was proactively offered to all MSM presenting at the center. CT/NG screening rates, test positivity rates and case detection rates in the years 2018 and 2019 were compared to those in the years 2016 and 2017.

resultsA total of 234 patients were enrolled in the study contributing to 798.7 patient years (py) during the four-year study period. Screening rates increased from 3.1% and 3.9% in 2016 and 2017 to 51.1% in 2018 and decrease to 35.4% in 2019. Over the study period, 19.7% (46/234) had at least one positive CT/NG result. After the intervention, case detection per 100 py increased for CT (2016: 2.6, 2017: 3.7, 2018: 7.7, 2019: 7.1) and NG (2016: 3.2, 2017: 3.1, 2018: 5.3, 2019: 7.6). The number needed to test was 8.9 for CT and 10.4 for NG.

conclusionRegular CT/NG screening is feasible in a primary care setting, leads to an increase in case detection and may contribute to decrease transmission and complications of CT/NG.

trial registrationThe trial is registered in ClinicalTrials.gov (NCT02149004).

Indexed as

Chlamydia InfectionsGonorrheaHIV InfectionsSexual and Gender MinoritiesChlamydia trachomatisCohort StudiesFollow-Up StudiesHomosexuality, MaleHumansIncidenceMaleNeisseria gonorrhoeaePrevalencePrimary Health CareReinfectionRisk FactorsHIVMSMPrimary careSTI incidenceSTI screening

Identifiers

PMID36352322
PMCPMC10352398

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.