Evidence map›Paper›PMID 36352245›Full record

ArticleScientific reports2022

Behavioral signatures of Y-like neuronal responses in human vision.

Ana L Ramirez, Lowell W Thompson, Ari Rosenberg, Curtis L Baker

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ana L RamirezDepartment of Ophthalmology & Visual Sciences, McGill University, McGill Vision Research, 1650 Cedar Ave, Room L11.112, Montreal, QC, H3G 1A4, Canada.
Lowell W ThompsonDepartment of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Ari RosenbergDepartment of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Curtis L BakerDepartment of Ophthalmology & Visual Sciences, McGill University, McGill Vision Research, 1650 Cedar Ave, Room L11.112, Montreal, QC, H3G 1A4, Canada. curtis.baker@mcgill.ca.
McGill University · CAUniversity of Wisconsin–Madison · US

Funding

Hierarchical cortical circuits implementing robust 3D visual perceptionR01EY029438 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Ari Rosenberg · 2018 to 2026
$3.8M
Neuroscience Training ProgramT32NS105602 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Ari Rosenberg · 2019 to 2026
$2.5M
Natural Sciences and Engineering Research Council of Canada OPG0001978NEI NIH HHS R01 EY029438NINDS NIH HHS T32 NS105602
6 · The paper itself

Abstract

Retinal ganglion cells initiating the magnocellular/Y-cell visual pathways respond nonlinearly to high spatial frequencies (SFs) and temporal frequencies (TFs). This nonlinearity is implicated in the processing of contrast modulation (CM) stimuli in cats and monkeys, but its contribution to human visual perception is not well understood. Here, we evaluate human psychophysical performance for CM stimuli, consisting of a high SF grating carrier whose contrast is modulated by a low SF sinewave envelope. Subjects reported the direction of motion of CM envelopes or luminance modulation (LM) gratings at different eccentricities. The performance on SF (for LMs) or carrier SF (for CMs) was measured for different TFs (LMs) or carrier TFs (CMs). The best performance for LMs was at lower TFs and SFs, decreasing systematically with eccentricity. However, performance with CMs was bandpass with carrier SF, largely independent of carrier TF, and at the highest carrier TF (20 Hz) decreased minimally with eccentricity. Since the nonlinear subunits of Y-cells respond better at higher TFs compared to the linear response components and respond best at higher SFs that are relatively independent of eccentricity, these results suggest that behavioral tasks employing CM stimuli might reveal nonlinear contributions of retinal Y-like cells to human perception.

Indexed as

Retinal Ganglion CellsVisual PathwaysAnimalsCatsContrast SensitivityHumansPhotic Stimulation

Identifiers

PMID36352245
PMCPMC9646870
OpenAlexW4308624722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.