Evidence map›Paper›PMID 36351993›Full record

ReviewScientific reports2022

Identification of Relevant Attributes for Liver Cancer Therapies (IRALCT): a maximum-difference-scaling analysis.

Bennet Hensen, Carolin Winkelmann, Frank K Wacker, Bodo Vogt, Cornelia L A Dewald, Thomas Neumann

Open access · goldAbstract readReview
In one paragraph

Review in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bennet Hensen *Research Campus STIMULATE, Otto von Guericke University Magdeburg, Otto-Hahn-Straße 2, 39106, Magdeburg, Germany.
Carolin Winkelmann *Research Campus STIMULATE, Otto von Guericke University Magdeburg, Otto-Hahn-Straße 2, 39106, Magdeburg, Germany.
Frank K WackerResearch Campus STIMULATE, Otto von Guericke University Magdeburg, Otto-Hahn-Straße 2, 39106, Magdeburg, Germany.
Bodo VogtResearch Campus STIMULATE, Otto von Guericke University Magdeburg, Otto-Hahn-Straße 2, 39106, Magdeburg, Germany.
Cornelia L A Dewald *Department of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany. dewald.cornelia@mh-hannover.de.ORCID 0000-0001-8805-2291
Thomas Neumann *Research Campus STIMULATE, Otto von Guericke University Magdeburg, Otto-Hahn-Straße 2, 39106, Magdeburg, Germany.
Medizinische Hochschule Hannover · DEOtto-von-Guericke-Universität Magdeburg · DEUniversity of Siegen · DE

Funding

PRACTIS - Clinician Scientist Program ME 3696/3-1Research Campus STIMULATE 13GW0095A
6 · The paper itself

Abstract

The Identification of Relevant Attributes for Liver Cancer Therapies (IRALCT) project is intended to provide new insights into the relevant utility attributes regarding therapy choices for malignant primary and secondary liver tumors from the perspective of those who are involved in the decision-making process. It addresses the potential value of taking patients' expectations and preferences into account during the decision-making and, when possible, adapting therapies according to these preferences. Specifically, it is intended to identify the relevant clinical attributes that influence the patients', medical laymen's, and medical professionals' decisions and compare the three groups' preferences. We conducted maximum difference (MaxDiff) scaling among 261 participants (75 physicians, 97 patients with hepatic malignancies, and 89 medical laymen) to rank the importance of 14 attributes previously identified through a literature review. We evaluated the MaxDiff data using count analysis and hierarchical Bayes estimation (HB). Physicians, patients, and medical laymen assessed the same 7 attributes as the most important: probability (certainty) of a complete removal of the tumor, probability of reoccurrence of the disease, pathological evidence of tumor removal, possible complications during the medical intervention, welfare after the medical intervention, duration and intensity of the pain, and degree of difficulty of the medical intervention. The cumulative relative importance of these 7 attributes was 88.3%. Our results show that the physicians', patients', and medical laymen's preferences were very similar and stable.Trial registration DRKS-ID of the study: DRKS00013304, Date of Registration in DRKS: 2017/11/16.

Indexed as

Liver NeoplasmsPhysiciansBayes TheoremHumansResearch Design

Identifiers

PMID36351993
PMCPMC9646805
OpenAlexW4308627317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.