Evidence map›Paper›PMID 36351696›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2023

Synergistic Protection against Secondary Pneumococcal Infection by Human Monoclonal Antibodies Targeting Distinct Epitopes.

Aaron D Gingerich, Fredejah Royer, Anna L McCormick, Anna Scasny, Jorge E Vidal, Jarrod J Mousa

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Clinical microbiology reviews · 2025
    Review
  2. Microbiology spectrum · 2025
    Article
  3. Article
  4. Article
  5. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
  6. Article
  7. Antibodies as drugs-a Keystone Symposia report.Annals of the New York Academy of Sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aaron D GingerichCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA.
Fredejah RoyerCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA.ORCID 0000-0003-3012-2431
Anna L McCormickCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA.
Anna ScasnyDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS; and.ORCID 0000-0003-3567-1157
Jorge E VidalDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS; and.ORCID 0000-0003-0573-5658
Jarrod J MousaCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA; jarrod.mousa@uga.edu.ORCID 0000-0003-4709-2478
University of Georgia · USUniversity of Mississippi Medical Center · US

Funding

PREP at University of GeorgiaR25GM109435 · NIGMS · UNIVERSITY OF GEORGIA · PI DOLAN, ERIN L, KLONOWSKI, KIMBERLY D. · 2014 to 2024
$3.4M
Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infectionR01AI173084 · NIAID · UNIVERSITY OF GEORGIA · PI MOUSA, JARROD · 2023 to 2025
$2.2M
Therapeutic antibodies to treat Pneumocystis pneumonia in a nonhuman primate model of HIV infectionK01OD026569 · OD · UNIVERSITY OF GEORGIA · PI MOUSA, JARROD · 2018 to 2020
$1.0M
HEMOGLOBIN-INDUCED VIRULENCE IN STREPTOCOCCUSPNEUMONIAER21AI151571 · NIAID · UNIVERSITY OF MISSISSIPPI MED CTR · PI AKERLEY, BRIAN, EICHENBAUM, ZEHAVA · 2021 to 2022
$441k
NIAID NIH HHS R01 AI173084NIAID NIH HHS R21 AI151571NIGMS NIH HHS R25 GM109435NIH HHS K01 OD026569
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pneumococcal InfectionsStreptococcus pneumoniaeAnimalsAntibodies, BacterialAntibodies, MonoclonalBacterial ProteinsEpitopesHumansLungMicePneumococcal VaccinesAntibodies, BacterialAntibodies, MonoclonalBacterial ProteinsEpitopesPneumococcal Vaccines

Identifiers

PMID36351696
PMCPMC9898123
OpenAlexW4308683080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.