Evidence map›Paper›PMID 36351372›Full record

ArticleImmunity2022

An embarrassment of riches: RORγt

Emmanuel Stephen-Victor, Talal A Chatila

Abstract readComment
In one paragraph

Article in Immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Regulatory T cells in dominant immunologic tolerance.The Journal of allergy and clinical immunology · 2024
    Review
  5. Article
  6. Regulatory T cells in allergic inflammation.Seminars in immunology · 2023
    Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Emmanuel Stephen-VictorHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Talal A ChatilaDivision of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: talal.chatila@childrens.harvard.edu.

Funding

Immunological and Microbial Mechanisms in Food AllergyR01AI126915 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Talal Amine Chatila, Seth Rakoff-Nahoum · 2017 to 2026
$4.9M
Targeting microbial dysbiosis in Food Allergy to restore toleranceR01AI158814 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHATILA, TALAL AMINE, RAKOFF-NAHOUM, SETH · 2021 to 2025
$3.0M
NIAID NIH HHS R01 AI126915
6 · The paper itself

Abstract

RORγt

Indexed as

Nuclear Receptor Subfamily 1, Group F, Member 3Peripheral ToleranceAntigen-Presenting CellsEmbarrassmentForkhead Transcription FactorsImmune ToleranceTh17 CellsT-Lymphocytes, RegulatoryForkhead Transcription FactorsNuclear Receptor Subfamily 1, Group F, Member 3

Identifiers

PMID36351372
PMCPMC10069454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.