ArticleScience advances2022
Nickel-catalyzed switchable asymmetric electrochemical functionalization of alkenes.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Tunable enantioselective electrocatalytic functionalization of unactivated alkenes.Nature communications · 2026Article
- Enantioselective electrochemical nickel-catalyzed vinylogous radical reactions.Science advances · 2025Article
- Electrochemically Driven Nickel-Catalyzed Enantioselective Hydro-Arylation/Alkenylation of Enones.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Enantioselective nickel-catalyzed anodic oxidative dienylation and allylation reactions.Nature communications · 2024Article
- Asymmetric C-H Dehydrogenative Alkenylation via a Photo-induced Chiral α‑Imino Radical Intermediate.Nature communications · 2024Article
- Catalytic stereodivergent allylic alkylation of 2-acylimidazoles for natural product synthesis.Nature communications · 2023Article
- Cu-catalyzed asymmetric regiodivergent electrosynthesis and its application in the enantioselective total synthesis of (-)-fumimycin.Nature communications · 2023Article
- Metal-free electrochemical dihydroxylation of unactivated alkenes.Nature communications · 2023Article
- Electrochemical Late-Stage Functionalization.Chemical reviews · 2023Review
- Nickel/biimidazole-catalyzed electrochemical enantioselective reductive cross-coupling of aryl aziridines with aryl iodides.Nature communications · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of general electrocatalytic methods for the diversity-oriented regio- and stereoselective functionalization of alkenes remains a challenge in organic synthesis. We present a switchable electrocatalytic method based on anodic oxidative activation for the controlled liberation of chiral α-keto radical species toward stereoselective organic transformations. Electrogenerated α-keto radical species capture alkene partners, allowing switchable intermolecular alkene difunctionalization and alkenylation in a highly stereoselective manner. In addition to acting as proton donors to facilitate H
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