Evidence map›Paper›PMID 36350627›Full record

ArticleNucleic acids research2023

NLRscape: an atlas of plant NLR proteins.

Eliza C Martin, Catalin F Ion, Florin Ifrimescu, Laurentiu Spiridon, Jaap Bakker, Aska Goverse, Andrei-J Petrescu

Abstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Deciphering the Molecular Interplay Between RXLR-EncodedInternational journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review of protein structure-based analyses that illuminate plant stress mechanisms.Computational and structural biotechnology journal · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eliza C MartinDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Bucharest 060031, Romania.
Catalin F IonDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Bucharest 060031, Romania.
Florin IfrimescuDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Bucharest 060031, Romania.
Laurentiu SpiridonDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Bucharest 060031, Romania.
Jaap BakkerLaboratory of Nematology, Wageningen University and Research, Wageningen 6700ES, The Netherlands.
Aska GoverseLaboratory of Nematology, Wageningen University and Research, Wageningen 6700ES, The Netherlands.ORCID 0000-0002-7399-8743
Andrei-J PetrescuDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Bucharest 060031, Romania.ORCID 0000-0002-4478-3946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NLRscape is a webserver that curates a collection of over 80 000 plant protein sequences identified in UniProtKB to contain NOD-like receptor signatures, and hosts in addition a number of tools aimed at the exploration of the complex sequence landscape of this class of plant proteins. Each entry gathers sequence information, domain and motif annotations from multiple third-party sources but also in-house advanced annotations aimed at addressing caveats of the existing broad-based annotations. NLRscape provides a top-down perspective of the NLR sequence landscape but also services for assisting a bottom-up approach starting from a given input sequence. Sequences are clustered by their domain organization layout, global homology and taxonomic spread-in order to allow analysis of how particular traits of an NLR family are scattered within the plant kingdom. Tools are provided for users to locate their own protein of interest in the overall NLR landscape, generate custom clusters centered around it and perform a large number of sequence and structural analyses using included interactive online instruments. Amongst these, we mention: taxonomy distribution plots, homology cluster graphs, identity matrices and interactive MSA synchronizing secondary structure and motif predictions. NLRscape can be found at: https://nlrscape.biochim.ro/.

Indexed as

NLR ProteinsPlant ProteinsAmino Acid SequenceAscomycotaAtlases as TopicPlantsSoftwareWeb BrowserNLR ProteinsPlant Proteins

Identifiers

PMID36350627
PMCPMC9825502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.