Evidence map›Paper›PMID 36350574›Full record

ArticleInternational journal of epidemiology2023

Maternal age and the risk of low birthweight and pre-term delivery: a pan-Nordic comparison.

Siddartha Aradhya, Anna Tegunimataka, Øystein Kravdal, Pekka Martikainen, Mikko Myrskylä, Kieron Barclay, Alice Goisis

Open access · hybridAbstract read
In one paragraph

Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Siddartha AradhyaDemography Unit and Department of Sociology, Stockholm University, Stockholm, Sweden.ORCID 0000-0003-3748-6270
Anna TegunimatakaCentre for Economic Demography, Lund University, Lund, Sweden.
Øystein KravdalDepartment of Economics, University of Oslo, Oslo, Norway.
Pekka MartikainenMax Planck Institute for Demographic Research, Rostock, Germany.ORCID 0000-0001-9374-1438
Mikko MyrskyläMax Planck Institute for Demographic Research, Rostock, Germany.
Kieron BarclayDemography Unit and Department of Sociology, Stockholm University, Stockholm, Sweden.ORCID 0000-0002-5142-8467
Alice GoisisSocial Research Institute, University College London, London, UK.
Statistics Sweden · SEUniversity of Helsinki · FINorwegian Institute of Public Health · NOStockholm University · SEUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced maternal age at birth is considered a risk factor for adverse birth outcomes. A recent study applying a sibling design has shown, however, that the association might be confounded by unobserved maternal characteristics.

methodsUsing total population register data on all live singleton births during the period 1999-2012 in Denmark (N = 580 133; 90% population coverage), Norway (N = 540 890) and Sweden (N = 941 403) and from 2001-2014 in Finland (N = 568 026), we test whether advanced maternal age at birth independently increases the risk of low birthweight (LBW) (<2500 g) and pre-term birth (<37 weeks gestation). We estimated within-family models to reduce confounding by unobserved maternal characteristics shared by siblings using three model specifications: Model 0 examines the bivariate association; Model 1 adjusts for parity and sex; Model 2 for parity, sex and birth year.

resultsThe main results (Model 1) show an increased risk in LBW and pre-term delivery with increasing maternal ages. For example, compared with maternal ages of 26-27 years, maternal ages of 38-39 years display a 2.2, 0.9, 2.1 and 2.4 percentage point increase in the risk of LBW in Denmark, Finland, Norway and Sweden, respectively. The same patterns hold for pre-term delivery.

conclusionsAdvanced maternal age is independently associated with higher risk of poor perinatal health outcomes even after adjusting for all observed and unobserved factors shared between siblings.

Indexed as

Infant, Low Birth WeightAdultBirth WeightFemaleHumansInfant, NewbornMaternal AgeParityPregnancyRisk Factorsbirth outcomesMaternal age at birthNordic countriessibling design

Identifiers

PMID36350574
PMCPMC9908063
OpenAlexW4308635249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.