Evidence map›Paper›PMID 36350402›Full record

ArticleApplied microbiology and biotechnology2022

Protease or Clostridium butyricum addition to a low-protein diet improves broiler growth performance.

Tinghui Wang, Huayun Ling, Wei Zhang, Ying Zhou, Youguo Li, Yongmei Hu, Nan Peng, Shumiao Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Protease andAnimals : an open access journal from MDPI · 2025
    Article
  6. Use ofInsects · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Microbial proteases and their applications.Frontiers in microbiology · 2023
    Review
  13. Regulatory Effects of the ProbioticThe journal of poultry science · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tinghui Wang *State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Huayun Ling *State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Wei ZhangWuhan SunHY Biology Co., Ltd, Wuhan, 430206, People's Republic of China.
Ying ZhouWuhan SunHY Biology Co., Ltd, Wuhan, 430206, People's Republic of China.
Youguo LiState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Yongmei HuState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Nan PengState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Shumiao ZhaoState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China. shumiaozhao@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0001-6047-8880
Huazhong Agricultural University · CNWuhan Science and Technology Bureau · CN

Funding

Key Research and Development Project of Hubei Province 2020BBA054Key Research and Development Project of Hubei Province No.2020BBB065
6 · The paper itself

Abstract

Low-protein (LP) feeds are used in the poultry industry to combat the increasing consumption of protein resources and reduce environmental pollution caused by excessive nitrogen excretion. Dietary supplementation of protease or Clostridium butyricum increases the growth performance of broilers; however, it is unclear whether they counteract the negative effects of LP diets. The effects of protease and C. butyricum on growth performance, intestinal morphology, anti-oxidant capacity, anti-inflammatory response, and microbial community of broilers have not been studied extensively. Here, 450 healthy 1-day-old Cobb500 broilers were allocated to five groups, according to different diets: basal diet (Control); LP diet (LP; 2% less crude protein than the control); LP diet + 200 g/t HuPro protease (LPH); LP diet + 1.0 × 10

Indexed as

Clostridium butyricumAnimal FeedAnimalsAnti-Bacterial AgentsChickensDietDiet, Protein-RestrictedPeptide HydrolasesAnti-Bacterial AgentsPeptide HydrolasesBroilerClostridium butyricumGrowth performanceIntestinal healthLow-protein feedProtease

Identifiers

PMID36350402
OpenAlexW4308605048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.