Evidence map›Paper›PMID 36350150›Full record

ArticleMicrobiology spectrum2022

Self-Reported Long COVID and Its Association with the Presence of SARS-CoV-2 Antibodies in a Danish Cohort up to 12 Months after Infection.

Kamille Fogh, Tine Graakjær Larsen, Cecilie B Hansen, Rasmus B Hasselbalch, Alexandra R R Eriksen, Henning Bundgaard, Ruth Frikke-Schmidt, Linda M Hilsted, Lars Østergaard, Isik S Johansen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Long Covid Defined.The New England journal of medicine · 2024
    Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Kamille FoghDepartment of Cardiology, Copenhagen University Hospitalgrid.4973.9, Herlev and Gentofte, Denmark.ORCID 0000-0002-6669-6894
Tine Graakjær LarsenDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Cecilie B HansenLaboratory of Molecular Medicine, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.
Rasmus B HasselbalchDepartment of Cardiology, Copenhagen University Hospitalgrid.4973.9, Herlev and Gentofte, Denmark.
Alexandra R R EriksenDepartment of Cardiology, Copenhagen University Hospitalgrid.4973.9, Herlev and Gentofte, Denmark.
Henning BundgaardDepartment of Cardiology, Copenhagen University Hospitalgrid.4973.9, Rigshospitalet, Copenhagen, Denmark.
Ruth Frikke-SchmidtDepartment of Clinical Biochemistry, Copenhagen University Hospitalgrid.4973.9, Rigshospitalet, Copenhagen, Denmark.
Linda M HilstedDepartment of Clinical Medicine, Copenhagen University Hospitalgrid.4973.9, Faculty of Health and Medical Sciences, Copenhagen, Denmark.
Lars ØstergaardDepartment of Infectious Diseases, Aarhus University Hospitalgrid.154185.c Aarhus, Denmark.
Isik S JohansenDepartment of Infectious Diseases, Odense University Hospitalgrid.7143.1, Odense, Denmark.
Ida HagemanMental Health Services, Copenhagen, Denmark.
Peter GarredLaboratory of Molecular Medicine, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-2876-8586
Kasper IversenDepartment of Cardiology, Copenhagen University Hospitalgrid.4973.9, Herlev and Gentofte, Denmark.
Copenhagen University Hospital · DKAarhus University · DKMental Health Services · DKStatens Serum Institut · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of long coronavirus disease (COVID) symptoms are not specific to COVID-19 and could be explained by other conditions. The present study aimed to explore whether Danish individuals with a perception that they suffer from long COVID have antibodies against the nucleocapsid antigen, as a proxy for detecting previous infection. The study was conducted in February and March 2021, right after the second surge of the COVID-19 pandemic in Denmark. All members of the social media group on Facebook "Covidramte med senfølger" ("long COVID sufferers'') above the age of 17 years and living in Denmark were invited to participate in a short electronic questionnaire about long COVID risk factors and symptoms. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein was detected in blood samples as a proxy for natural SARS-CoV-2 infection. The final study population comprised 341 participants (90.6% females) who completed blood sampling and answered the questionnaire. A total of 232 (68%) were seropositive (median age, 49.5 years; interquartile range [IQR], 41 to 55 years; 90.1% females). There was no significant difference between sexes and serostatus. Seronegative and seropositive individuals had a similar burden of symptoms that could be attributed to long COVID. Time since perceived COVID-19 was significantly longer in the group of seronegative individuals than the seropositive ones (

Indexed as

COVID-19Post-Acute COVID-19 SyndromeAdolescentAntibodies, ViralCohort StudiesDenmarkFemaleHumansMaleMiddle AgedPandemicsSARS-CoV-2Self ReportAntibodies, Viralantibodieslong COVIDN proteinnucleocapsid antigenPASCpost-acute-phase COVID-19post-COVID syndromeprolonged COVIDSARS-CoV-2SARS-CoV-2 antibodies

Identifiers

PMID36350150
PMCPMC9769646
OpenAlexW4308639847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.