Evidence map›Paper›PMID 36350133›Full record

ArticleApplied and environmental microbiology2022

Characterization of the Biosynthetic Gene Cluster and Shunt Products Yields Insights into the Biosynthesis of Balmoralmycin.

Guang-Lei Ma, Lingyi Xin, Yanghui Liao, Zhi-Soon Chong, Hartono Candra, Li Mei Pang, Sean Qiu En Lee, Martin Muthee Gakuubi, Siew Bee Ng, Zhao-Xun Liang

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Guang-Lei MaSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Lingyi XinSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Yanghui LiaoSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Zhi-Soon ChongSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Hartono CandraSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Li Mei PangSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Sean Qiu En LeeSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Martin Muthee GakuubiSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.
Siew Bee NgSingapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore.
Zhao-Xun LiangSchool of Biological Sciences, Nanyang Technological Universitygrid.59025.3b, Singapore, Singapore.ORCID 0000-0002-3128-1330
Nanyang Technological University · SGAgency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angucyclines are a family of structurally diverse, aromatic polyketides with some members that exhibit potent bioactivity. Angucyclines have also attracted considerable attention due to the intriguing biosynthetic origins that underlie their structural complexity and diversity. Balmoralmycin (compound 1) represents a unique group of angucyclines that contain an angular benz[

Indexed as

PolyketidesStreptomycesAnthracyclinesBiosynthetic PathwaysCell Line, TumorHumansMultigene FamilyPolyketide SynthasesAnthracyclinesbalmoralmycinPolyketidesPolyketide Synthasesbiosynthesisbiosynthetic gene clusternatural productpolyketidespolyketide synthaseStreptomyces

Identifiers

PMID36350133
PMCPMC9746310
OpenAlexW4308637689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.