Evidence map›Paper›PMID 36349868›Full record

ArticleFuture medicinal chemistry2022

2-hydroxy-1,4-naphthoquinones with 3-alkyldiarylether groups: synthesis and

Amanda Berg, Chelsea B Swartchick, Noah Forrest, Matthew Chavarria, Madeleine C Deem, Alyson N Sillin, Yuexin Li, Teresa M Riscoe, Aaron Nilsen, Michael K Riscoe and 1 more

Open access · greenAbstract read
In one paragraph

Article in Future medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Amanda BergDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.
Chelsea B SwartchickDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.ORCID 0000-0003-0828-168X
Noah ForrestDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.
Matthew ChavarriaDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.
Madeleine C DeemDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.
Alyson N SillinDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.
Yuexin LiPortland VA Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA.
Teresa M RiscoePortland VA Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA.ORCID 0000-0003-0219-6417
Aaron NilsenPortland VA Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA.ORCID 0000-0002-3827-8222
Michael K RiscoePortland VA Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA.ORCID 0000-0002-1343-5279
Warren Jl WoodDepartment of Chemistry & Biochemistry, University of Portland, 5000 N. Willamette Blvd., Portland, OR 97203, USA.ORCID 0000-0001-8678-8473
University of Portland · USPortland VA Medical Center · USOregon Health & Science University · US

Funding

Optimizing ELQs for Treatment and Prevention of MalariaR01AI100569 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Michael Kevin RISCOE · 2014 to 2026
$8.0M
Development of a Sustained Release Injectable Formulation for Long-Term Delivery of ELQsR01AI141412 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI RISCOE, MICHAEL KEVIN · 2019 to 2022
$3.2M
BLRD VA I01 BX003312NIAID NIH HHS R01 AI100569NIAID NIH HHS R01 AI141412
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntimalarialsNaphthoquinonesHumansPlasmodium falciparumAntimalarialslawsoneNaphthoquinones2-hydroxy-1,4-naphthoquinonesmalariaPlasmodium falciparumradical alkylationthree-component reductive alkylation

Identifiers

PMID36349868
PMCPMC9832320
OpenAlexW4308638650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.