Evidence map›Paper›PMID 36349764›Full record

ArticleAmerican journal of nephrology2022

Trends in Adherence to Recommended Physical Activity and Its Association with Mortality and Disease Progression among US Adults with Chronic Kidney Disease.

Xiaolin Qu, Xin Tong, Xiaoxiang Hou, Junhui Zhang, Lijun Hou, Jigang Chen

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Article in American journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. PAG Masked Protective Physical Exercise-Induced High HIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolin QuDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Xin TongBeijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xiaoxiang HouDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Junhui ZhangEndocrinology Department, Southwest Hospital, Third Military Medical University, Chongqing, China.
Lijun HouDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Jigang ChenBeijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to examine the trends in adherence to the Physical Activity Guidelines (PAG) for aerobic activity and sedentary time and their effects on mortality and disease progression among US adults with chronic kidney disease (CKD).

methodsWe studied individuals from the National Health and Nutrition Examination Survey 2007-08 to 2017-18 with a mortality file in 2015. Multivariate regression models were used to evaluate the association between adherence to PAG and sedentary time with mortality, estimated glomerular filtration rate (eGFR), and urine albumin-to-creatinine ratio.

resultsFor the CKD population, adherence rate increased from 48.2% in 2007-08 to 55.0% in 2017-18, and sedentary time peaked in 2013-14 (7.5 h/day) and then decreased afterward. There was no difference in the trends across the non-CKD and CKD population. For the CKD population, adherence to the PAG was significantly associated with all-cause mortality (HR, 0.49; 95% CI: 0.38-0.63), malignant neoplasm mortality (HR, 0.30; 95% CI: 0.17-0.52), and albumin-creatinine ratio (OR, -0.27; 95% CI: -0.39 to -0.15). Sedentary time was significantly associated with all-cause mortality (HR, 1.12; 95% CI: 1.08-1.15), heart disease mortality (HR, 1.13; 95% CI: 1.08-1.19), and eGFR (OR, -0.49; 95% CI: -0.72 to -0.26).

conclusionsFavorable trends were observed in adherence to the PAG and sedentary time. Adherence to the PAG and reduction in sedentary time reduced all-cause and cause-specific mortality and prevented disease progression differently. Efforts are needed to decrease sedentary time rather than adhering to the PAG for aerobic activity alone.

Indexed as

Renal Insufficiency, ChronicAdultAlbuminsCreatinineDisease ProgressionExerciseGlomerular Filtration RateHumansNutrition SurveysRisk FactorsAlbuminsCreatinineChronic kidney diseaseMortalityPhysical activity

Identifiers

PMID36349764
PMCPMC9808653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.