Evidence map›Paper›PMID 36349405›Full record

ArticleAngewandte Chemie (International ed. in English)2023

Structurally Defined Water-Soluble Metallofullerene Derivatives towards Biomedical Applications.

Yanbang Li, Rohin Biswas, William P Kopcha, Thierry Dubroca, Laura Abella, Yue Sun, Ryan A Crichton, Christopher Rathnam, Letao Yang, Yao-Wen Yeh and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Theoretical Studies of Non-Metal Endohedral Fullerenes.Nanomaterials (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Fullerene CInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Synthesis and characterization of water-soluble CBeilstein journal of organic chemistry · 2024
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Yanbang LiDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Rohin BiswasDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
William P KopchaDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Thierry DubrocaNational High Magnetic Field Laboratory (NHMFL), Florida State University, 1800 E. Paul Dirac Dr., Tallahassee, FL 32310, USA.
Laura AbellaDepartament de Química Física i Inorgànica, Universitat Rovira i Virgili, Marcel⋅lí Domingo 1, 43007, Tarragona, Spain.
Yue SunDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Ryan A CrichtonDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Christopher RathnamDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Letao YangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Yao-Wen YehDepartment of Physics and Astronomy, Rutgers, The State University of New Jersey, 136 Frelinghuysen Rd, Piscataway, NJ 08854, USA.
Krishnendu KunduNational High Magnetic Field Laboratory (NHMFL), Florida State University, 1800 E. Paul Dirac Dr., Tallahassee, FL 32310, USA.
Antonio Rodríguez-ForteaDepartament de Química Física i Inorgànica, Universitat Rovira i Virgili, Marcel⋅lí Domingo 1, 43007, Tarragona, Spain.
Josep M PobletDepartament de Química Física i Inorgànica, Universitat Rovira i Virgili, Marcel⋅lí Domingo 1, 43007, Tarragona, Spain.
Ki-Bum LeeDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.
Stephen HillNational High Magnetic Field Laboratory (NHMFL), Florida State University, 1800 E. Paul Dirac Dr., Tallahassee, FL 32310, USA.
Jianyuan ZhangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 123 Bevier Rd, Piscataway, NJ 08854, USA.ORCID 0000-0002-2919-2734
Rutgers, The State University of New Jersey · USFlorida State University · USUniversitat Rovira i Virgili · ES

Funding

Machine learning-enabled Comparative Transcriptomic Profiling to Validate NanoScript-induced Inner Ear Hair CellsR01DC016612 · NIDCD · RUTGERS, THE STATE UNIV OF N.J. · PI KWAN, KELVIN Y., LEE, KIBUM · 2018 to 2022
$2.8M
Nanoparticle-based synthetic transcription factor to induce stem cell myogenesisR21AR071101 · NIAMS · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM · 2017 to 2018
$371k
NIAMS NIH HHS R21 AR071101NIDCD NIH HHS R01 DC016612NIH Office of the Director R21AR071101
6 · The paper itself

Abstract

Endohedral metallofullerenes (EMFs) are excellent carriers of rare-earth element (REE) ions in biomedical applications because they preclude the release of toxic metal ions. However, existing approaches to synthesize water-soluble EMF derivatives yield mixtures that inhibit precise drug design. Here we report the synthesis of metallobuckytrio (MBT), a three-buckyball system, as a modular platform to develop structurally defined water-soluble EMF derivatives with ligands by choice. Demonstrated with PEG ligands, the resulting water-soluble MBTs show superb biocompatibility. The Gd MBTs exhibit superior T

Indexed as

FullerenesContrast MediaLigandsContrast MediaFullerenesLigandsContrast AgentsEndohedral FullerenesRare Earth CompoundsSupramolecular ChemistrySynthesis Design

Identifiers

PMID36349405
PMCPMC9983306
OpenAlexW4308638534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.