Evidence map›Paper›PMID 36349194›Full record

ArticleOpen medicine (Warsaw, Poland)2022

Relationship of plasma MBP and 8-oxo-dG with brain damage in preterm.

Yuwei Zhao, Guanghui Liu, Lei Liang, Zaiwei Yu, Jian Zhang, Hong Zheng, Liying Dai

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuwei ZhaoNeonatology Department, Anhui Provincial Children Hospital, Hefei, China.
Guanghui LiuNeonatology Department, Anhui Provincial Children Hospital, Hefei, China.
Lei LiangPulmonary Department, Anhui Provincial Children Hospital, Hefei, China.
Zaiwei YuNeonatology Department, Fuyang First People's Hospital, Fuyang, China.
Jian ZhangNeonatology Department, Anhui Provincial Children Hospital, Hefei, China.
Hong ZhengNeonatology Department, Anhui Provincial Children Hospital, Hefei, China.
Liying DaiNeonatology Department, Anhui Provincial Children Hospital, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm infants face a significant risk of brain injury in the perinatal period, as well as potential long-term neurodevelopmental disabilities. However, preterm children with brain injury lack specific clinical manifestations in the early days. Therefore, timely and accurate diagnosis of brain injury is of vital importance. This study was to explore the diagnostic efficiency of myelin basic protein (MBP) and 8-oxo-deoxyguanosine (8-oxo-dG) serum levels in brain injury of premature infants. A total of 75 preterm infants with gestational age between 28 and 32 weeks and birth weight higher than 1,000 g were prospectively included. MBP serum levels were significantly higher in premature infants with white matter injury (WMI). 8-oxo-dG serum levels were significantly increased in both WMI and periventricular-intraventricular hemorrhages (PIVH). MBP and 8-oxo-dG were significantly correlated. The area under the curve was 0.811 [95% confidence interval (CI) 0.667-0.955;

Indexed as

8-oxo-deoxyguanosinebrain injurymyelin basic proteinperiventricular–intraventricular hemorrhagespreterm infantswhite matter injury

Identifiers

PMID36349194
PMCPMC9587527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.