Evidence map›Paper›PMID 36348346›Full record

ArticleTrials2022

Conducting a supportive oncology clinical trial during the COVID-19 pandemic: challenges and strategies.

Jie Deng, John N Lukens, Joy C Cohn, Erin McMenamin, Barbara Murphy, Bryan A Spinelli, Niya Murphy, Alicia K Steinmetz, Megan A Landriau, Alexander Lin

Registry-linked trialAbstract readLetter
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03030859 (Self-Care for Head and Neck Cancer Survivors With Lymphedema and Fibrosis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03030859 nacompletednot on this map

Self-Care for Head and Neck Cancer Survivors With Lymphedema and Fibrosis

TypeinterventionalSponsorUniversity of PennsylvaniaRan2018 to 2022Enrolled59ConditionsHead and Neck Cancer, Lymphedema, FibrosisArmsUsual Care, Usual Care plus LEF-SCP, Usual Care plus LEF-SCP plus Follow-up
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Research staff's experiences of how the COVID-19 pandemic impacted recruitment for a paediatric network study.International journal of qualitative studies on health and well-being · 2024
    Article
  3. Supportive oncology in a cancer center: development of a novel department (2017-2021).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jie DengUniversity of Pennsylvania, Philadelphia, PA, USA. jiedeng@nursing.upenn.edu.ORCID http://orcid.org/0000-0002-2553-8822
John N LukensUniversity of Pennsylvania, Philadelphia, PA, USA.
Joy C CohnUniversity of Pennsylvania, Philadelphia, PA, USA.
Erin McMenaminUniversity of Pennsylvania, Philadelphia, PA, USA.
Barbara MurphyVanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Bryan A SpinelliThomas Jefferson University, Philadelphia, PA, USA.
Niya MurphyUniversity of Pennsylvania, Philadelphia, PA, USA.
Alicia K SteinmetzUniversity of Pennsylvania, Philadelphia, PA, USA.
Megan A LandriauUniversity of Pennsylvania, Philadelphia, PA, USA.
Alexander LinUniversity of Pennsylvania, Philadelphia, PA, USA.

Funding

American Cancer Society RSG-16-207-01-PCSM
6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic resulted in severe interruptions to clinical research worldwide. This global public health crisis required investigators and researchers to rapidly develop and implement new strategies and solutions to mitigate its negative impact on the progress of clinical trials. In this paper, we describe the challenges, strategies, and lessons learned regarding the continuation of a supportive oncology clinical trial during the pandemic. We hope to provide insight into the implementation of clinical trials during a public health emergency to be better prepared for future instances.Trial registration: ClinicalTrials.gov, a service of the US National Institute of Health (NCT03030859). Registered on 22 January 2017.

Indexed as

COVID-19NeoplasmsHumansMedical OncologyPandemicsSARS-CoV-2Clinical trialsCOVID-19FibrosisHead and neck cancerLymphedemaPandemicParticipant safetyTelehealthTrial operationVirtual visits

Identifiers

PMID36348346
PMCPMC9640795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.