Evidence map›Paper›PMID 36348301›Full record

ArticleBMC bioinformatics2022

An interpretable DIC risk prediction model based on convolutional neural networks with time series data.

Hao Yang, Jiaxi Li, Siru Liu, Mengjiao Zhang, Jialin Liu

Open access · goldAbstract read
In one paragraph

Article in BMC bioinformatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Artificial intelligence in clinical thrombosis and hemostasis: A review.Research and practice in thrombosis and haemostasis · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hao Yang *Information Center, West China Hospital, Sichuan University, Chengdu, China.
Jiaxi Li *Department of Clinical Laboratory Medicine, Jinniu Maternity and Child Health Hospital of Chengdu, Chengdu, China.
Siru LiuDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Mengjiao ZhangInformation Center, West China Hospital, Sichuan University, Chengdu, China.
Jialin LiuInformation Center, West China Hospital, Sichuan University, Chengdu, China. Dljl8@163.com.
Sichuan University · CNMaternal and Child Health Hospital of Sichuan Province · CNVanderbilt University Medical Center · US

Funding

Sichuan Health Informatics Society 20222016
6 · The paper itself

Abstract

Disseminated intravascular coagulation (DIC) is a complex, life-threatening syndrome associated with the end-stage of different coagulation disorders. Early prediction of the risk of DIC development is an urgent clinical need to reduce adverse outcomes. However, effective approaches and models to identify early DIC are still lacking. In this study, a novel interpretable deep learning based time series is used to predict the risk of DIC. The study cohort included ICU patients from a 4300-bed academic hospital between January 1, 2019, and January 1, 2022. Experimental results show that our model achieves excellent performance (AUC: 0.986, Accuracy: 95.7%, and F1:0.935). Gradient-weighted Class Activation Mapping (Grad-CAM) was used to explain how predictive models identified patients with DIC. The decision basis of the model was displayed in the form of a heat map. The model can be used to identify high-risk patients with DIC early, which will help in the early intervention of DIC patients and improve the treatment effect.

Indexed as

Disseminated Intravascular CoagulationCohort StudiesHumansNeural Networks, ComputerTime FactorsDisseminated intravascular coagulationMachine learningPrediction

Identifiers

PMID36348301
PMCPMC9644626
OpenAlexW4308573977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.