ArticleBMC ophthalmology2022
Diabetic retinopathy and corneal endothelial parameters: an analytical cross-sectional study.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05838898 (Changes of Corneal Endothelial Cells in Patients With PDR Using Specular Microscopy), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes of Corneal Endothelial Cells in Patients With PDR Using Specular Microscopy
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Corneal endothelial changes in type 2 diabetes mellitus: a systematic review and meta-analysis with subgroup comparisons by diabetic retinopathy status and disease duration.Frontiers in endocrinology · 2026Pooled it
- Specular microscopy findings in diabetic patients: a systematic review and meta-analysis.Clinical diabetes and endocrinology · 2024Review
- Ferrous ascorbate as a potential biomarker for diabetic retinopathy: a vitreous humour metabolomics study.BMC ophthalmology · 2024Article
- Comparative assessment of the corneal endothelium following phacoemulsification surgery in patients with type II diabetes and nondiabetes.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Study of Correlation of Severity of Diabetic Retinopathy with Corneal Thickness and Endothelial Parameter Changes in Diabetic Patients.Romanian journal of ophthalmologyReview
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the possible association of different pattern of diabetic retinopathy (DR) on corneal endothelium cells in type 2 diabetes mellitus patients.
methodsIn this descriptive-analytical cross-sectional study, corneal endothelium parameters including endothelial cell density (ECD), average cell size (AVG), coefficient of variation in cell size (CV), and hexagonality (Hex) were evaluated by non-contact specular microscopy.
resultsOne hundred and thirty-four eyes of 134 diabetic patients including 77 females (57.5%) with a mean age of 61.03 ± 8.08 years were enrolled. The overall corneal parameters in diabetic patients with and without retinopathy were not significantly different (P > 0.05). There is a significant relationship between CV and the duration of the disease with age variable control (B = 0.369, p-value < 0.001).
conclusionsCorneal endothelial parameters were not associated with DM in patients without and with DR. There is a significant relationship between CV and the duration of the disease with age variable control.
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Registered trials
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