ArticleOphthalmology and therapy2023
The Effect of Meibomian Gland Dysfunction on Laser-Assisted In Situ Keratomileusis in Asymptomatic Patients.
Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Clinical analysis of dry eye after refractive surgery in army recruits in 2024.Scientific reports · 2025Article
- Use of oral retinoids in the perioperative period by surgical specialty: a literature review.Archives of dermatological research · 2025Review
- Long-Term Evaluation of Ocular Surface and Meibomian Gland Function after Laser-Assisted in situ Keratomileusis Surgery.Ophthalmic research · 2025Article
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Authors and funding
6 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionTo evaluate the impact of asymptomatic meibomian gland dysfunction (MGD) on laser-assisted in situ keratomileusis (LASIK) outcomes and dry eye signs and symptoms.
methodsA retrospective analysis of patients who underwent LASIK surgery between July 2017 and February 2018 at Care Vision Refractive Clinic, Tel Aviv, Israel, was done. Patients were divided into those who had preoperative asymptomatic significant MGD (MGD group) and those who did not have preoperative significant MGD (control group). Outcomes were the postoperative presence of punctate epithelial erosions, dry eye symptoms, the number of postoperative visits as a measure of adverse events, visual acuity, spherical equivalent, safety index, efficacy index, and the type of refractive error (myopia or hyperopia).
resultsA total of 497 eyes were included in this study. Both groups had similar rates of punctate epithelial erosions, 30 (12.9%) patients vs. 39 patients (14.8%) (p = 0.31); postoperative complaints of dryness, 75 patients (32.3%) vs. 90 patients (34.2%) (p = 0.36); and postoperative number of visits, 3.15 ± 0.75 vs. 3.12 ± 0.54 (p = 0.59). Uncorrected visual acuity (logMAR) at 1 month (0.026 ± 0.09 vs. 0.026 ± 0.17, p = 0.99) after surgery was similar in both groups. Mean spherical equivalent was 0.03 ± 0.17 and - 0.03 ± 0.18 (p = 0.99) in both groups. Safety index was 1.024 ± 0.06 in the clinically significant MGD group and 1.029 ± 0.07 in the control group (p = 0.45). Efficacy index was also similar in both groups (0.966 ± 0.155 and 0.979 ± 0.14, respectively, p = 0.31). No differences were found between patients with myopia and hyperopia.
conclusionsPatients with preoperative asymptomatic MGD have similar LASIK outcomes to patients without preoperative asymptomatic MGD. Accordingly, no preoperative MGD treatment or special caution is needed in these cases.
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