Evidence map›Paper›PMID 36348168›Full record

ArticleSurgical endoscopy2023

Ten-year outcomes following ventral hernia repair: making the case for better post-market surveillance in the USA.

Dahlia M Kenawy, Jennifer M Underhill, Ayanna G Jacobs, Molly A Olson, Savannah M Renshaw, Benjamin T Gabanic, Marlene I Garcia-Neuer, Parviz Kanga, Aysenur Gunacar, Benjamin K Poulose

Abstract read
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Mapping the therapeutic landscape in emergency incisional hernia: a scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dahlia M KenawyCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA. dahlia.kenawy@osumc.edu.ORCID 0000-0002-6096-9978
Jennifer M UnderhillCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Ayanna G JacobsCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Molly A OlsonDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Savannah M RenshawCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Benjamin T GabanicCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Marlene I Garcia-NeuerCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Parviz KangaCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Aysenur GunacarCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.
Benjamin K PouloseCenter for Abdominal Core Health, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, #670, Columbus, OH, 43210, USA.

Funding

Advanced Research Training in Immunology for Surgery Trainees (ARTIST)T32AI106704 · NIAID · OHIO STATE UNIVERSITY · PI GINNY L BUMGARDNER, Jon R Wisler · 2014 to 2026
$3.5M
NIAID NIH HHS T32 AI106704
6 · The paper itself

Abstract

backgroundWe sought to identify the 10-year complication and recurrence rates and associated sociodemographic and operative characteristics associated with non-mesh versus mesh-based ventral hernia repairs (VHRs).

methodsThis was an IRB-approved (2020H0317) retrospective longitudinal study of patients undergoing mesh or non-mesh VHR from 2009-2019 at a single tertiary-care institution. The electronic medical record was used to collect sociodemographic, clinical, and intraoperative details, and early (≤ 30 days) and long-term (> 30-day) postoperative complications. Up to ten-year follow-up was obtained for long-term complications, categorized as: hernia recurrence reoperation (HRR), major complications requiring emergency surgery (MCES) (defined as non-elective operations related to the abdominal wall), and non-recurrence procedural intervention (NRPI) (defined as any procedures related to the abdominal wall, bowel, or mesh). Kaplan-Meier survival curves were obtained for each long-term complication.

resultsOf the 645 patients identified, the mean age at index operation was 52.51 ± 13.57 years with 50.70% female. Of the index operations, 21.24% were for a recurrence. Procedure categories included: 57.36% incisional, 37.21% non-incisional umbilical, 8.22% non-incisional epigastric, 3.88% parastomal, 0.93% diastasis recti, and 0.47% Spigelian hernias. Operative approaches included open (n = 383), laparoscopic (n = 267), and robotic (n = 21). Fascial closure (81.55%) and mesh use (66.2%) were performed in the majority of cases. Median follow-up time was 2098 days (interquartile range 1320-2806). The rate of short-term complications was 4.81% for surgical site infections, 15.04% for surgical site occurrences, and 13.64% for other complications. At 10 years, the HRR-free survival probability was 85.26%, MCES-free survival probability was 94.44%, and NRPI-free survival probability was 78.11%.

conclusionsA high proportion of patients experienced long-term recurrence and complications requiring intervention after index VHR. For many patients, a ventral hernia develops into a chronic medical condition. Improved efforts at post-market surveillance of operative approaches and mesh location and type should be undertaken to help optimize outcomes.

Indexed as

Hernia, VentralAbdominal WallAdultAgedFemaleHerniorrhaphyHumansIncisional HerniaLaparoscopyLongitudinal StudiesMaleMiddle AgedRetrospective StudiesSurgical MeshSurgical Wound InfectionAbdominal wallEmergency general surgeryMesh complicationsVentral hernia recurrence

Identifiers

PMID36348168
PMCPMC10164834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.