Evidence map›Paper›PMID 36348038›Full record

ArticleScientific reports2022

Infrared nanospectroscopic imaging of DNA molecules on mica surface.

Irma Custovic, Nicolas Pocholle, Eric Bourillot, Eric Lesniewska, Olivier Piétrement

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Irma CustovicLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, Université de Bourgogne-Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon Cedex, France.
Nicolas PocholleLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, Université de Bourgogne-Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon Cedex, France.
Eric BourillotLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, Université de Bourgogne-Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon Cedex, France.
Eric LesniewskaLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, Université de Bourgogne-Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon Cedex, France.
Olivier PiétrementLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, Université de Bourgogne-Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon Cedex, France. olivier.pietrement@u-bourgogne.fr.ORCID 0000-0002-0018-7202

Funding

CNRS Mission pour l'Interdisciplinarité MI-DynAFM-DNARep 2018_273085EIPHI Graduate School ANR-17-EURE-0002Région Bourgogne-Franche-Comté AAP Région 2020 DNA-Heritage
6 · The paper itself

Abstract

Significant efforts have been done in last two decades to develop nanoscale spectroscopy techniques owning to their great potential for single-molecule structural detection and in addition, to resolve open questions in heterogeneous biological systems, such as protein-DNA complexes. Applying IR-AFM technique has become a powerful leverage for obtaining simultaneous absorption spectra with a nanoscale spatial resolution for studied proteins, however the AFM-IR investigation of DNA molecules on surface, as a benchmark for a nucleoprotein complexes nanocharacterization, has remained elusive. Herein, we demonstrate methodological approach for acquisition of AFM-IR mapping modalities with corresponding absorption spectra based on two different DNA deposition protocols on spermidine and Ni

Indexed as

Aluminum SilicatesDNAMicroscopy, Atomic ForceNucleoproteinsSpectrophotometry, InfraredAluminum SilicatesDNAmicaNucleoproteins

Identifiers

PMID36348038
PMCPMC9643503

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.