ArticleDiabetologia2023
Kidney function measures and cardiovascular outcomes in people with diabetes: the Hoorn Diabetes Care System cohort.
Article in Diabetologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Sex Differences in the Cardiovascular Significance of Albuminuria in Type 2 Diabetes: A Narrative Review.Journal of clinical medicine · 2026Review
- LCN2 Associated With the Bidirectional Cardio-Kidney Link in Patients With Type 2 Diabetes and Cardiovascular-Kidney-Metabolic Syndrome.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Article
- Linear association between atherogenic index of plasma and diabetic kidney disease: evidence from a large clinical cohort and NHANES.Frontiers in nutrition · 2026Article
- Significant association between elevated urine albumin-to-creatinine ratio and increased risk of acute coronary syndrome: a retrospective cross-sectional analysis.Annals of medicine · 2025Article
- Association of atherogenic index of plasma with kidney dysfunction in diabetic individuals: findings from two national population-based studies.BMC endocrine disorders · 2025Article
- Associations between kidney function with all-cause and cause-specific mortality in type 2 diabetes mellitus patients: a prospective cohort study in China.Journal of health, population, and nutrition · 2025Article
- Association of Kidney Function With 10-Year Risk of Atherosclerotic Cardiovascular Disease, Cardiovascular Disease and Its Risk Factors Among Women With Type 2 Diabetes Mellitus.International journal of women's health · 2025Article
- Association between measures of kidney function and preserved ratio impaired spirometry in diabetes: NHANES 2007-2012.BMJ open · 2024Article
- Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients.Endocrine · 2024Article
- Are There Any Pleiotropic Benefits of Vitamin D in Patients With Diabetic Kidney Disease? A Systematic Review of Randomized Controlled Trials.Canadian journal of kidney health and disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
aims/hypothesisBoth manifestations of kidney disease in diabetes, reduced eGFR (ml/min per 1.73 m
methodsWe assessed the prospective association between annually recorded measures of eGFR and UACR and the occurrence of myocardial infarction (MI), CHD, stroke, heart failure (HF) and cardiovascular mortality in 13,657 individuals with diabetes (53.6% male, age 62.3±12.1 years) from the Hoorn Diabetes Care System cohort, using data obtained between 1998 and 2018. Multivariate time-dependent Cox regression models adjusted for cardiovascular risk factors were used to estimate HRs and 95% CI. Associations of eGFR were adjusted for UACR values and vice versa. Effect modification by sex was investigated for all associations.
resultsAfter a mean follow-up period of 7 years, event rates per 1000 person-years were 3.08 for MI, 3.72 for CHD, 1.12 for HF, 0.84 for stroke and 6.25 for cardiovascular mortality. Mildly reduced eGFR (60-90 ml/min per 1.73 m CONCLUSIONS/
interpretationThis study showed differential and independent prospective associations between manifestations of early kidney damage in diabetes and several CVD subtypes, suggesting that regular monitoring of both kidney function measures may help to identify individuals at higher risk of specific cardiovascular events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.