Evidence map›Paper›PMID 36347890›Full record

ArticleNature communications2022

Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3.

Luciano G Dolce, Aubree A Zimmer, Laura Tengo, Félix Weis, Mary Anne T Rubio, Juan D Alfonzo, Eva Kowalinski

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Two codes of RNA editing by deamination in human diseases.Experimental & molecular medicine · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Structural basis of tRNA recognition by the mNature structural & molecular biology · 2024
    Article
  13. ADATs: roles in tRNA editing and relevance to disease.Acta biochimica et biophysica Sinica · 2024
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Luciano G DolceEMBL Grenoble, 71 Avenue des Martyrs, 38042, Grenoble, France.
Aubree A ZimmerDepartment of Microbiology and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.
Laura TengoEMBL Grenoble, 71 Avenue des Martyrs, 38042, Grenoble, France.ORCID 0000-0002-6883-6459
Félix WeisEMBL Heidelberg, Structural and Computational Biology Unit, Meyerhofstraße 1, 69117, Heidelberg, Germany.ORCID 0000-0002-8137-3532
Mary Anne T RubioDepartment of Microbiology and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-2202-5239
Juan D AlfonzoDepartment of Microbiology and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-8503-3316
Eva KowalinskiEMBL Grenoble, 71 Avenue des Martyrs, 38042, Grenoble, France. kowalinski@embl.fr.ORCID 0000-0002-9785-9027
European Molecular Biology Laboratory · FRThe Ohio State University · US

Funding

tRNA editing by deamination: Balancing affinity and specifictyR01GM084065 · NIGMS · OHIO STATE UNIVERSITY · PI ALFONZO, JUAN D · 2008 to 2021
$4.0M
Cellular, molecular, and biochemical sciences training grantT32GM141955 · NIGMS · OHIO STATE UNIVERSITY · PI Jane Elizabeth Jackman, JESSE J KWIEK · 2021 to 2026
$2.2M
NIGMS NIH HHS R01 GM084065NIGMS NIH HHS T32 GM141955
6 · The paper itself

Abstract

The essential deamination of adenosine A

Indexed as

Adenosine DeaminaseEukaryotaAnticodonInosineRNA, TransferAdenosine DeaminaseAnticodonInosineRNA, Transfer

Identifiers

PMID36347890
PMCPMC9643335
OpenAlexW4308541754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.