ArticleNature communications2022
GZMK
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 63 papers.
0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 90 citations in OpenAlex.
- Radiotherapy and immunotherapy in cancer treatment: mechanisms of clinical synergy.The Journal of clinical investigation · 2026Review
- PD-1⁺ CD8⁺ T cells: roles of PD-1 beyond an exhaustion marker.Seminars in immunopathology · 2026Review
- Manufacturing synthetic viscoelastic antigen-presenting cells for immunotherapy.Nature protocols · 2026Review
- NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme KImmunity · 2026Article
- Investigating the expression of CTLA-4 and CD28 genes as immune regulators in patients with colorectal polyps.BMC cancer · 2026Article
- Clonal embeddings allow exploratory analysis of lineage-resolved single-cell data.bioRxiv : the preprint server for biology · 2026Article
- Integrated single-cell transcriptomic atlas of human gastric and colorectal tissues across diverse phenotypes.Scientific data · 2026Article
- KLRG1 defines a distinct tumor-infiltrating granzyme K+ CD8 + T cell population.Journal of cancer research and clinical oncology · 2026Article
- Colorectal microenvironment determines the prognosis of colorectal cancer.Experimental & molecular medicine · 2026Article
- Spatiotemporal dynamics of tumor-associated neutrophils: bridging the gap between cancer progression and immunotherapy.Molecular cancer · 2026Review
- ZNF683Nature communications · 2026Article
- Extracellular granzyme K enhances PD-L1 transcription and stability via F2RL1 activation to facilitate tumor immune evasion in lung adenocarcinoma.Journal for immunotherapy of cancer · 2026Article
- Unraveling Signaling Pathways in Immune Microenvironment Crosstalk to Overcome Immunotherapy Resistance in Colorectal Cancer.Human mutation · 2026Review
- Single-Cell Transcriptomics Reveals the Potential Role of GZMK+ CD8+ T Cells in Cell Senescence of Triple-Negative Breast Cancer.International journal of genomics · 2026Article
- Neutrophil extracellular traps: the hidden driver of gastrointestinal cancer and emerging therapeutic strategies.Frontiers in immunology · 2026Review
- The CXCL12-CXCR4 axis in colorectal cancer: immune regulation, metastatic progression, and therapeutic implications.Frontiers in immunology · 2026Review
- Metabolic dysfunction and GZMKFrontiers in immunology · 2026Review
- Integrated single-cell TCR analysis across tissue identifies GZMKInternational journal of biological sciences · 2026Article
- CEBPB-Regulated Gastric Cell Plasticity Promotes Liver Metastasis of Gastric Cancer.Cancer communications (London, England) · 2026Article
- Ageing, immune fitness and cancer.Nature reviews. Cancer · 2025Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
28 authors at 8 institutions in 2 countries.
Silvia TibertiDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.
Carlotta CatozziDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0002-1028-1489
Ottavio CrociCenter for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milano, Italy.
Mattia BalleriniDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.
Danilo CagninaDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0001-5701-935X
Chiara SorianiDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0003-4363-6597
Caterina ScirgoleaLaboratory of Translational Immunology, IRCCS- Humanitas Research Hospital-, Milan, Italy.ORCID 0000-0001-9213-5532
Zheng GongThe Jackson Laboratory, Bar Harbor, ME, USA.
Jiatai HeThe Jackson Laboratory, Bar Harbor, ME, USA.
Angeli D MacandogDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.
Amir NabinejadDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0003-3276-1368
Carina B Nava LausonDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.
Arianna Quinte'Department of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.
Giovanni BertalotDepartment of Pathology, APSS Trento Hospital & Health Care, Trento, Italy.
Wanda L PetzDigestive Surgery Division, European Institute of Oncology-IRCCS, Milan, Italy.
Simona P RavendaDivision of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology-IRCCS, Milan, Italy.
Valerio LicursiInstitute of Molecular Biology and Pathology (IBPM), National Research Council (CNR) of Italy, Rome, Italy.ORCID 0000-0002-8172-1437
Paola PaciDepartment of Computer, Control and Management Engineering, Sapienza - University of Rome, Rome, Italy.ORCID 0000-0002-9393-2047
Marco RasponiDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.ORCID 0000-0002-2904-8652
Luca RottaDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0001-6915-1120
Nicola FazioDigestive Surgery Division, European Institute of Oncology-IRCCS, Milan, Italy.
Guangwen RenThe Jackson Laboratory, Bar Harbor, ME, USA.ORCID 0000-0003-2436-9593
Uberto Fumagalli-RomarioDigestive Surgery Division, European Institute of Oncology-IRCCS, Milan, Italy.ORCID 0000-0002-6865-8971
Martin H SchaeferDepartment of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy.ORCID 0000-0001-7503-6364
Stefano CampanerCenter for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milano, Italy.
Enrico LugliLaboratory of Translational Immunology, IRCCS- Humanitas Research Hospital-, Milan, Italy.ORCID 0000-0002-1964-7678
Luigi Nezi *Department of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy. luigi.nezi@ieo.it.ORCID 0000-0002-4670-7656
Teresa Manzo *Department of Experimental Oncology, European Institute of Oncology- IRCCS, Milano, Italy. teresa.manzo@ieo.it.ORCID 0000-0001-8552-3625
European Institute of Oncology · ITJackson Laboratory · USIRCCS Humanitas Research Hospital · ITItalian Institute of Technology · ITInstitute of Molecular Biology and Pathology · ITPolitecnico di Milano · ITProvincia Autonoma di Trento · ITSapienza University of Rome · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
CD8
Indexed as
CD8-Positive T-LymphocytesColorectal NeoplasmsHumansLymphocytes, Tumor-InfiltratingNeutrophils
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.