Evidence map›Paper›PMID 36347382›Full record

ReviewNeuroscience and biobehavioral reviews2022

Sex, love and oxytocin: Two metaphors and a molecule.

C Sue Carter

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Oxytocin.Current biology : CB · 2025
    Review
  5. Review
  6. Oxytocin, Vasopressin and Stress: A Hormetic Perspective.Current issues in molecular biology · 2025
    Review
  7. The psychedelic-peptide paradox: a hormetic hypothesis.Comprehensive psychoneuroendocrinology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Fantastic voyage:Comprehensive psychoneuroendocrinology · 2024
    Review
  12. Article
  13. Oxytocin: A developmental journey.Comprehensive psychoneuroendocrinology · 2023
    Review
  14. Review
  15. Review
  16. Close encounters with oxytocin.Comprehensive psychoneuroendocrinology · 2023
    Review
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

C Sue CarterDepartment of Psychology, University of Virginia, Charlottesville, VA 22904, USA; Kinsey Institute, Indiana University, Bloomington, IN 47405, USA. Electronic address: suecarterporges@gmail.com.

Funding

Mechanisms of maternal brain changes with birth interventionsR01HD098117 · NICHD · UNIVERSITY OF VIRGINIA · PI JESSICA J CONNELLY, Allison M. Perkeybile · 2019 to 2026
$4.9M
ImagingP01HD075750 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI CARTER PORGES, CAROL SUE · 2014 to 2018
$4.3M
Modeling Immune Desensitization in Renal TransplantationR01AI098112 · NIAID · UNIVERSITY OF ROCHESTER · PI ZAND, MARTIN S · 2012 to 2016
$1.9M
NIAID NIH HHS R01 AI098112NICHD NIH HHS P01 HD075750NICHD NIH HHS R01 HD098117
6 · The paper itself

Abstract

Dozens of studies, most conducted in the last four decades, have implicated oxytocin, as well as vasopressin and their receptors, in processes that mediate selective sociality and the consequences of early experience. Oxytocin is critical for the capacity to experience emotional safety and healthy sexuality. Oxytocin also plays a central role in almost every aspect of physical and mental health, including the coordination of sociality and loving relationships with physiological reactions to challenges across the lifespan. Species, including prairie voles, that share with humans the capacity for selective social bonds have been a particularly rich source of insights into the behavioral importance of peptides. The purpose of this historical review is to describe the discovery of a central role for oxytocin in behavioral interactions associated with love, and in the capacity to use sociality to anticipate and cope with challenges across the lifespan - a process that here is called "sociostasis."

Indexed as

LoveOxytocinAnimalsArvicolinaeHumansMetaphorReceptors, OxytocinSocial BehaviorOxytocinReceptors, OxytocinAttachmentHistoryLoveOxytocinSexVasopressinVoles

Identifiers

PMID36347382
PMCPMC9759207

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.