ArticleProceedings of the National Academy of Sciences of the United States of America2022
Leveraging a natural murine meiotic drive to suppress invasive populations.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Highlighting the genetics of natural and synthetic selfish elements in a special GENETICS and G3 series.Genetics · 2026Article
- Article
- Highlighting the genetics of natural and synthetic selfish elements in a special GENETICS and G3 series.G3 (Bethesda, Md.) · 2026Article
- Y-linked editors for invasive rodent control.Molecular biology and evolution · 2026Article
- The LAST Mile: Evaluating Genetic Biocontrol as a Supplemental Tool for Eradicating Invasive Rodents on Islands.Evolutionary applications · 2026Article
- Assessing target genes for homing suppression gene drive.The EMBO journal · 2026Article
- Impacts of rodents in piggeries in Australia - review and pilot impact study.Pest management science · 2026Review
- Emerging trends in genome editing of wild animals.Transgenic research · 2026Review
- Leveraging DNA repair mechanisms in genetically engineered biocontrol.Current opinion in insect science · 2026Review
- Predicting the invasiveness of threshold-dependent gene drives.bioRxiv : the preprint server for biology · 2025Article
- Maximising Eradication Potential of Rat Gene Drives Using a Two-Target Homing Rescue Strategy: Spatial Modelling of Empirical Data.Molecular ecology · 2025Article
- Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus?BMC biology · 2024Article
- Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene.Nature communications · 2024Article
- Investigating the potential of X chromosome shredding for mouse genetic biocontrol.Scientific reports · 2024Article
- A framework for identifying fertility gene targets for mammalian pest control.Molecular ecology resources · 2024Article
- Genomic Tools in Biological Invasions: Current State and Future Frontiers.Genome biology and evolution · 2024Article
- Taking stock: Is gene drive research delivering on its principles?Gates open research · 2024Article
- Sex or poison? Genetic pest management in the 21st century.BMC biology · 2023Article
- Monosex Populations of the Giant Freshwater PrawnInternational journal of molecular sciences · 2023Review
- Manipulating the Destiny of Wild Populations Using CRISPR.Annual review of genetics · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invasive rodents are a major cause of environmental damage and biodiversity loss, particularly on islands. Unlike insects, genetic biocontrol strategies including population-suppressing gene drives with biased inheritance have not been developed in mice. Here, we demonstrate a gene drive strategy (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.