Evidence map›Paper›PMID 36346668›Full record

Trial reportJournal of medical Internet research2022

Personalized Prediction of Response to Smartphone-Delivered Meditation Training: Randomized Controlled Trial.

Christian A Webb, Matthew J Hirshberg, Richard J Davidson, Simon B Goldberg

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04426318 (COVID-19 and the Healthy Minds Program for Educators), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04426318 nacompletednot on this map

COVID-19 and the Healthy Minds Program for Educators

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2020 to 2021Enrolled698ConditionsAnxiety, Depression, Psychological Stress, Psychological DistressArmsHealthy Minds Program Foundations Training
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Does it matter how meditation feels? An experience sampling study.Journal of consulting and clinical psychology · 2024
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christian A WebbHarvard Medical School, Boston, MA, United States.ORCID 0000-0002-8310-4539
Matthew J HirshbergCenter for Healthy Minds, University of Wisconsin - Madison, Madison, WI, United States.ORCID 0000-0001-9070-1270
Richard J DavidsonCenter for Healthy Minds, University of Wisconsin - Madison, Madison, WI, United States.ORCID 0000-0002-8506-4964
Simon B GoldbergCenter for Healthy Minds, University of Wisconsin - Madison, Madison, WI, United States.ORCID 0000-0002-6888-0126
University of Wisconsin–Madison · USHarvard University · US

Funding

Neural Substrates of Affective Style and Emotion RegulationR01MH043454 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J, SCHAEFER, STACEY M · 1989 to 2022
$9.6M
Supplemental: Neural and cognitive propensity for trait rumination in adolescents: a multimodal study with ecological momentary assessments and MRIR01AT011002 · NCCIH · MCLEAN HOSPITAL · PI WEBB, CHRISTIAN ANTHONY · 2021 to 2025
$3.4M
Predicting the onset of depression in at-risk adolescents from endophenotype profilesR01MH116969 · NIMH · MCLEAN HOSPITAL · PI WEBB, CHRISTIAN ANTHONY · 2019 to 2024
$2.8M
The plasticity of well-being: A research network to define, measure and promote human flourishingU24AT011289 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2021 to 2024
$2.4M
Passive and Acquired Immunity to Cryptosporidiosis in Bangladeshi ChildrenK23AI108790 · NIAID · UNIVERSITY OF VIRGINIA · PI KORPE, POONUM S. · 2014 to 2018
$876k
Mindfulness training delivered via mobile health to reduce depression and anxietyK23AT010879 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI GOLDBERG, SIMON B · 2020 to 2024
$786k
NCCIH NIH HHS K23 AT010879NCCIH NIH HHS R01 AT011002NCCIH NIH HHS U24 AT011289NIAID NIH HHS K23 AI108790NIMH NIH HHS R01 MH043454NIMH NIH HHS R01 MH116969
6 · The paper itself

Abstract

backgroundMeditation apps have surged in popularity in recent years, with an increasing number of individuals turning to these apps to cope with stress, including during the COVID-19 pandemic. Meditation apps are the most commonly used mental health apps for depression and anxiety. However, little is known about who is well suited to these apps.

objectiveThis study aimed to develop and test a data-driven algorithm to predict which individuals are most likely to benefit from app-based meditation training.

methodsUsing randomized controlled trial data comparing a 4-week meditation app (Healthy Minds Program [HMP]) with an assessment-only control condition in school system employees (n=662), we developed an algorithm to predict who is most likely to benefit from HMP. Baseline clinical and demographic characteristics were submitted to a machine learning model to develop a "Personalized Advantage Index" (PAI) reflecting an individual's expected reduction in distress (primary outcome) from HMP versus control.

resultsA significant group × PAI interaction emerged (t

conclusionsOverall, the results revealed the potential of a data-driven algorithm to inform which individuals are most likely to benefit from a meditation app. Such an algorithm could be used to objectively communicate expected benefits to individuals, allowing them to make more informed decisions about whether a meditation app is appropriate for them.

trial registrationClinicalTrials.gov NCT04426318; https://clinicaltrials.gov/ct2/show/NCT04426318.

Indexed as

COVID-19MeditationMobile ApplicationsHumansPandemicsSmartphonemachine learningmeditationmobile phonemobile technologyprecision medicinepredictionsmartphone app

Identifiers

PMID36346668
PMCPMC9682449
OpenAlexW4297405122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.