Evidence map›Paper›PMID 36346614›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Multidimensional Cell-Free DNA Fragmentomic Assay for Detection of Early-Stage Lung Cancer.

Siwei Wang, Fanchen Meng, Ming Li, Hua Bao, Xin Chen, Meng Zhu, Rui Liu, Xiuxiu Xu, Shanshan Yang, Xue Wu and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07126626 (Multi-center Prospective Validation of the SPOT-MAS Lung Test Using Circulating Tumor DNA for the Detection of Lung Cancer), which is not on this map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07126626 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Multi-center Prospective Validation of the SPOT-MAS Lung Test Using Circulating Tumor DNA for the Detection of Lung Cancer

TypeobservationalSponsorGene SolutionsRan2025 to 2027Enrolled1,184ConditionsLung Diseases, Lung Cancer Screening
3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Trial
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  15. Observational
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Siwei WangDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research.ORCID 0000-0001-5077-060X
Fanchen MengDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research.
Ming LiDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research.
Hua BaoGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0001-5774-8755
Xin ChenGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0003-1871-4477
Meng ZhuSchool of Public Health and.ORCID 0000-0001-5122-1733
Rui LiuGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0002-1642-1243
Xiuxiu XuGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0003-4199-7874
Shanshan YangGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.
Xue WuGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0002-5567-1325
Yang ShaoGeneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.ORCID 0000-0003-4585-1792
Lin XuDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research.
Rong YinDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research.ORCID 0000-0002-9744-4251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell-Free Nucleic AcidsLung NeoplasmsBiomarkers, TumorHumansLungWhole Genome SequencingBiomarkers, TumorCell-Free Nucleic Acidscell-free DNAearly detectionlung cancermachine learningwhole-genome sequencing

Identifiers

PMID36346614
PMCPMC10161762

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.