Evidence map›Paper›PMID 36346574›Full record

ArticleHead and neck pathology2023

Mucosal Leishmaniasis of the lip: Report of an Exuberant case in a Young man.

José Alcides Almeida de Arruda, Saygo Tomo, John Lennon Silva Cunha, José Ramón Guevara, Idalina Martínez, Oscar Reyes, Verónica Bracho, Carlos Sanchez, Bruno Augusto Benevenuto de Andrade, Mariana Villarroel-Dorrego

Open access · greenAbstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

José Alcides Almeida de ArrudaDepartment of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Saygo TomoDepartment of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
John Lennon Silva CunhaDepartment of Oral Diagnosis, Piracicaba Dental School, Universidade Estadual de Campinas, Piracicaba, Brazil.
José Ramón GuevaraNational Programme of Leishmaniasis, Biomedicine Institute "Dr. Jacinto Convit", Caracas, Venezuela.
Idalina MartínezNational Programme of Leishmaniasis, Biomedicine Institute "Dr. Jacinto Convit", Caracas, Venezuela.
Oscar ReyesNational Programme of Leishmaniasis, Biomedicine Institute "Dr. Jacinto Convit", Caracas, Venezuela.
Verónica BrachoNational Programme of Leishmaniasis, Biomedicine Institute "Dr. Jacinto Convit", Caracas, Venezuela.
Carlos SanchezOral Medicine, Dental School, Universidad Central de Venezuela, Caracas, Venezuela.
Bruno Augusto Benevenuto de AndradeDepartment of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, R. Rodolpho Paulo Rocco, n. 325, 1st floor, Cidade Universitária, Rio de Janeiro, RJ, Brazil. brunoabandrade@ufrj.br.
Mariana Villarroel-DorregoOral Medicine, Dental School, Universidad Central de Venezuela, Caracas, Venezuela.ORCID http://orcid.org/0000-0002-3259-606X
Instituto Médico La Floresta · VECentral University of Venezuela · VEAC Camargo Hospital · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal do Rio de Janeiro · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundLeishmaniasis is a tropical disease caused by protozoan parasites of the genus Leishmania. Mucosal leishmaniasis has been described as secondary to the cutaneous form; however, isolated mucosal involvement can also occur. Specifically, mucosal leishmaniasis of the lip is poorly described and its diagnosis challenges clinicians.

methodsWe herein report a case of mucosal leishmaniasis affecting the lower lip without cutaneous involvement in a 20-year-old Venezuelan man. The patient had no relevant past medical history. Clinically, a mass-like lesion with ulcerations and crusts was observed.

resultsMicroscopically, the lesion was composed of granulomatous inflammation along with macrophages containing intracytoplasmic inclusions similar to round-shaped Leishmania. The species Leishmania (Viannia) braziliensis was confirmed. Treatment with meglumine antimonate was effective. The lesion healed satisfactorily, and no side effects or recurrences were observed.

conclusionClinicians should be aware of isolated forms of mucosal leishmaniasis of the lip, even in cases where the cutaneous lesion is undetected or clinically manifests as self-limiting. Knowing the endemic areas in the scenario of the dynamics of the ecoepidemiology of leishmaniasis is also essential for surveillance and counselling of the population.

Indexed as

Leishmania braziliensisLeishmaniasis, MucocutaneousAdultHumansLipMaleMeglumine AntimoniateSkinYoung AdultMeglumine Antimoniateinfectious diseasesleishmanialeishmaniasislipmeglumine antimonateneglected diseases

Identifiers

PMID36346574
PMCPMC10293522
OpenAlexW4308554572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.