Evidence map›Paper›PMID 36346472›Full record

Trial reportEuropean journal of nutrition2023

Self-selected meal composition alters the relationship between same-day caloric intake and appetite scores in humans during a long-term ad-libitum feeding study.

Angela M Horgan, Gundula R Palmbach, Julia M Jordan, Holly S Callahan, Kaatje E Meeuws, David S Weigle, Mario Kratz, Jonathan Q Purnell

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05002491 (Change in Leptin as a Predictor of Satiety With High Protein Feeding), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05002491 nacompletednot on this map

Change in Leptin as a Predictor of Satiety With High Protein Feeding

TypeinterventionalSponsorOregon Health and Science UniversityRan2002 to 2003Enrolled19ConditionsDietary ExposureArmsHigh protein diet
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Angela M HorganClinical Translational Research Center of the Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR, USA.
Gundula R PalmbachClinical Translational Research Center of the Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR, USA.
Julia M JordanClinical Translational Research Center of the Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR, USA.
Holly S CallahanInstitute of Translational Health Sciences, Seattle, WA, USA.
Kaatje E MeeuwsClinical Translational Research Center of the Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR, USA.
David S WeigleDivision of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Seattle, WA, USA.
Mario KratzCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Jonathan Q PurnellKnight Cardiovascular Institute and Division of Endocrinology, Diabetes, and Clinical Nutrition, Center for Preventive Cardiology, HRC5N, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA. purnellj@ohsu.edu.ORCID http://orcid.org/0000-0001-5505-6333
Oregon Health & Science University · USFred Hutch Cancer Center · USInstitute of Translational Health Sciences · USUniversity of Washington · US

Funding

METABOLIC CONSEQUENCES OF ANTIRETROVIRAL THERAPYR01DK055460 · NIDDK · UNIVERSITY OF WASHINGTON · PI WEIGLE, DAVID S · 1999 to 2003
$1.8M
CORTISOL, CENTRAL OBESITY, AND INSULIN RESISTANCEK23DK002689 · NIDDK · OREGON HEALTH AND SCIENCE UNIVERSITY · PI PURNELL, JONATHAN Q. · 2000 to 2003
$523k
STUDIES OF REGIONAL FAT DISTRIBUTION AND ENERGY BALANCEK24DK002860 · NIDDK · UNIVERSITY OF WASHINGTON · PI WEIGLE, DAVID S · 2001 to 2005
$486k
National Institutes of Health DK02689National Institutes of Health DK02860National Institutes of Health DK55460National Institutes of Health UL1-RR02319National Institutes of Health UL1-RR02369NIH HHS DK02689NIH HHS DK02860NIH HHS DK55460NIH HHS UL1-RR02319NIH HHS UL1-RR02369
6 · The paper itself

Abstract

purposeTo determine the effect of an off-protocol meal during a long-term ad libitum feeding study on changes in total caloric consumption and ratings of hunger and satiety.

methodsDuring the ad libitum portion of a 16 weeks research high-protein feeding study, 19 participants were allowed to eat up to one self-selected meal (SSM) a week instead of an intervention diet meal. The SSM was assessed for total caloric and macronutrient composition and compared to the intervention diet for 3 days before and after the SSM day. Visual analog scores rating daily hunger and fullness were collected and compared as well.

resultsOn the SSM day, the mean ± SD daily caloric intake increased by 262 ± 332 kcal compared to the previous study days (P < 0.001), with no changes in subjective appetite scores. The following day there was a slight but significant reduction in intake (- 58 ± 85 kcal, P = 0.008) compared to the average pre-SSM day with no change in appetite scores. On the SSM day, percent protein intake was inversely associated mean daily caloric intake (r

conclusionsDuring a long-term, ad-libitum high-protein feeding study, one SSM lower in protein increased daily total caloric consumption with no impact on appetite ratings and incomplete caloric consumption during subsequent days. These data suggest that during ad-libitum feeding, a single meal change in protein content impacts the relationships between daily level of hunger, satiety and calorie intake. CLINICALTRIALS: GOV ID: NCT05002491 (retrospectively registered 07/20/2021).

Indexed as

AppetiteEnergy IntakeCross-Over StudiesDietHumansHungerSatiationDiet fatDiet proteinEnergy intakeHungerMacronutrient compositionObesitySatiety

Identifiers

PMID36346472
OpenAlexW4308555760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.