Evidence map›Paper›PMID 36346465›Full record

ArticleArchives of microbiology2022

Discovery of enzymes to biotransform ginsenoside Rd into ginsenosides F2 and CK using metagenomics and genomic mining.

Rui Wang, Yong Lai, Qi Fang, Meiya Chen, Hui Lei, Can Song

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rui Wang *School of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Yong Lai *School of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Qi FangSchool of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Meiya ChenSchool of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Hui LeiSchool of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Can SongSchool of Pharmacy, Southwest Medical University, Luzhou, 646000, Sichuan, China. cansong@swmu.edu.cn.
Southwest Medical University · CN

Funding

the Applied Basic Research Cooperation Project of Luzhou Government-Southwest Medical University 2020LZXNYDJ28the Scientific Research Foundation for Talent Introduction of Southwest Medical University 0903-00040031
6 · The paper itself

Abstract

Ginsenosides are the main active components of ginseng, including many types and different contents. Among them, minor ginsenosides have better biological functions and pharmacological activities than those of the major ginsenosides. However, minor ginsenosides cannot be obtained in large quantities, but by means of enzymatic transformation technology, some major ginsenosides can be de-glycosylated at a specific position to generate minor ginsenosides. In this study, we report two glycosidase genes associated with the conversion of ginsenoside Rd to ginsenosides F

Indexed as

DeerGinsenosidesPanaxAnimalsbeta-GlucosidaseBiotransformationMetagenomicsbeta-Glucosidaseginsenoside F2ginsenoside RdGinsenosidesBiotransformationGene miningGinsenosideGlucosidaseMetagenomic

Identifiers

PMID36346465
OpenAlexW4308595839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.