Evidence map›Paper›PMID 36346250›Full record

ArticleAntimicrobial agents and chemotherapy2022

Pseudomonas aeruginosa Phosphate Transporter PitA (PA4292) Controls Susceptibility to Aminoglycoside Antibiotics by Regulating the Proton Motive Force.

Xinrui Zhao, Yongxin Jin, Fang Bai, Zhihui Cheng, Weihui Wu, Xiaolei Pan

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Adaptation to cinnamaldehyde shapesJournal of bacteriology · 2025
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  2. mBio · 2025
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  3. Article
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  6. Frontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xinrui ZhaoState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.
Yongxin JinState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.ORCID 0000-0002-1449-6735
Fang BaiState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.ORCID 0000-0003-0639-8104
Zhihui ChengState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.
Weihui WuState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.ORCID 0000-0002-9017-0091
Xiaolei PanState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai Universitygrid.216938.7, Tianjin, China.ORCID 0000-0003-0907-2177
Nankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes nosocomial infections in immunocompromised patients. β-lactam and aminoglycoside antibiotics are commonly used in the treatment of P. aeruginosa infections. Previously, we found that mutation in a

Indexed as

Proton-Motive ForcePseudomonas aeruginosaAdenosine TriphosphateAminoglycosidesAnti-Bacterial Agentsbeta-LactamsEscherichia coliPhosphatesPhosphate Transport ProteinsAdenosine TriphosphateAminoglycosidesAnti-Bacterial Agentsbeta-LactamsPhosphatesPhosphate Transport Proteinsaminoglycoside resistanceaminoglycosidesPA4292phosphate transportphosphate transporterPitAproton motive forcePseudomonas aeruginosa

Identifiers

PMID36346250
PMCPMC9765264
OpenAlexW4308507738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.