Evidence map›Paper›PMID 36346236›Full record

ArticlemSystems2022

Predicting Influenza A Virus Infection in the Lung from Hematological Data with Machine Learning.

Suneet Singh Jhutty, Julia D Boehme, Andreas Jeron, Julia Volckmar, Kristin Schultz, Jens Schreiber, Klaus Schughart, Kai Zhou, Jan Steinheimer, Horst Stöcker and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Suneet Singh Jhutty *Frankfurt Institute for Advanced Studiesgrid.417999.b, Frankfurt am Main, Germany.
Julia D Boehme *Immune Regulation Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Andreas JeronImmune Regulation Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Julia VolckmarImmune Regulation Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Kristin SchultzImmune Regulation Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Jens SchreiberDepartment of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburggrid.5807.a, Magdeburg, Germany.
Klaus SchughartDepartment of Infection Genetics, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Kai ZhouFrankfurt Institute for Advanced Studiesgrid.417999.b, Frankfurt am Main, Germany.
Jan SteinheimerFrankfurt Institute for Advanced Studiesgrid.417999.b, Frankfurt am Main, Germany.
Horst StöckerFrankfurt Institute for Advanced Studiesgrid.417999.b, Frankfurt am Main, Germany.
Sabine Stegemann-KoniszewskiDepartment of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburggrid.5807.a, Magdeburg, Germany.
Dunja BruderImmune Regulation Group, Helmholtz Centre for Infection Researchgrid.7490.a, Braunschweig, Germany.
Esteban A Hernandez-VargasFrankfurt Institute for Advanced Studiesgrid.417999.b, Frankfurt am Main, Germany.
Otto-von-Guericke University Magdeburg · DEFrankfurt Institute for Advanced Studies · DEHelmholtz Centre for Infection Research · DEGoethe University Frankfurt · DEGSI Helmholtz Centre for Heavy Ion Research · DEUniversity of Idaho · USUniversity of Tennessee Health Science Center · US

Funding

Sequence-structure-function relationships in human visual photopigmentsP20GM104420 · NIGMS · UNIVERSITY OF IDAHO · PI VAN LEUVEN, JAMES · 2015 to 2024
$22.9M
NIGMS NIH HHS P20 GM104420
6 · The paper itself

Abstract

The tracking of pathogen burden and host responses with minimally invasive methods during respiratory infections is central for monitoring disease development and guiding treatment decisions. Utilizing a standardized murine model of respiratory influenza A virus (IAV) infection, we developed and tested different supervised machine learning models to predict viral burden and immune response markers, i.e., cytokines and leukocytes in the lung, from hematological data. We performed independently

Indexed as

Influenza A virusInfluenza, HumanOrthomyxoviridae InfectionsRespiratory Tract InfectionsAnimalsCytokinesHumansInterferon-gammaLungMachine LearningMiceCytokinesInterferon-gammabiosystemscytokineshematological parametersimmune cellsinfectious diseaseinfluenzamachine learning

Identifiers

PMID36346236
PMCPMC9765554
OpenAlexW4308508206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.