ArticleeLife2022
An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Structure, assembly, and mechanism of the MmpL family of transporters.Microbiology and molecular biology reviews : MMBR · 2026Review
- Polar growth factor PgfA regulates polar peptidoglycan synthesis as well as mycolate synthesis inJournal of bacteriology · 2026Article
- A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance inScience advances · 2026Article
- Measuring Membrane Fluidity in Live Mycobacteria Reveals Subcellular Lateral Variation And Pole-Selective Responses to Mycomembrane Perturbation.ACS infectious diseases · 2026Article
- An activator of a two-component system controls cell separation and intrinsic drug resistance inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Contribution of Proteins to Membrane and Cell Wall Structures in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026Review
- Structures of MmpL complexes reveal the assembly and mechanism of this family of transporters.Science advances · 2025Article
- An activator of a two-component system controls cell separation and intrinsic drug resistance inbioRxiv : the preprint server for biology · 2025Article
- Evolutionarily divergent Mycobacterium tuberculosis CTP synthase filaments are under selective pressure.Nature communications · 2025Article
- A Photoactivatable Free Mycolic Acid Probe to Investigate Mycobacteria-Host Interactions.ACS infectious diseases · 2025Article
- Article
- TheFrontiers in microbiology · 2025Article
- MmpL3, Wag31, and PlrA are involved in coordinating polar growth with peptidoglycan metabolism and nutrient availability.Journal of bacteriology · 2024Article
- MmpL3, Wag31 and PlrA are involved in coordinating polar growth with peptidoglycan metabolism and nutrient availability.bioRxiv : the preprint server for biology · 2024Article
- An intramolecular cross-talk in D29 mycobacteriophage endolysin governs the lytic cycle and phage-host population dynamics.Science advances · 2024Article
- Spatial segregation and aging of metabolic processes underlie phenotypic heterogeneity in mycobacteria.bioRxiv : the preprint server for biology · 2023Article
- Role of succinyl substituents in the mannose-capping of lipoarabinomannan and control of inflammation in Mycobacterium tuberculosis infection.PLoS pathogens · 2023Article
- Recent advances in mycobacterial membrane protein large 3 inhibitor drug design for mycobacterial infections.Expert opinion on drug discovery · 2023Review
- Chemical approaches to unraveling the biology of mycobacteria.Cell chemical biology · 2023Review
- Polar protein Wag31 both activates and inhibits cell wall metabolism at the poles and septum.Frontiers in microbiology · 2022Article
Corrections and comments
- Commented on byUneven division.2023
Authors and funding
10 authors at 3 institutions in 1 country.
Kuldeepkumar R Gupta *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0001-7625-4224
Celena M Gwin *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-8928-7970
Kathryn C RahlwesDepartment of Microbiology, University of Massachusetts, Amherst, United States.
Kyle J BiegasDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, United States.
Chunyan WangDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.
Jin Ho ParkDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.
Jun LiuDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0003-3108-6735
Benjamin M SwartsDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, United States.
Yasu S MoritaDepartment of Microbiology, University of Massachusetts, Amherst, United States.
E Hesper RegoDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-2973-8354
Yale University · USCentral Michigan University · USUniversity of Massachusetts Boston · US
Funding
Structure-Function Relationships in the Spirochetal Flagellar MotorR01AI087946 · NIAID · YALE UNIVERSITY · PI LIU, JUN · 2010 to 2025
$6.6MStructural basis of phage infection and DNA ejectionR01GM110243 · NIGMS · YALE UNIVERSITY · PI LIU, JUN, MOLINEUX, IAN J · 2014 to 2024
$3.1M"The molecular mechanisms of asymmetric cell division in mycobacteria."R01AI148255 · NIAID · YALE UNIVERSITY · PI REGO, ELIZABETH HESPER · 2020 to 2024
$2.1MNIAID NIH HHS R01 AI087946NIAID NIH HHS R01 AI148255NIGMS NIH HHS R01 GM110243
Abstract
Mycobacteria, including the human pathogen
Indexed as
Mycobacterium tuberculosisPeriplasmic ProteinsCell MembraneHumansMycolic AcidsPeriplasmMycolic AcidsPeriplasmic Proteinscell divisiondrug targetsinfectious diseasemicrobiologymycobacteriaphenotypic heterogeneitypolar growth
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.