ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2023
Dysbiosis and reduced small intestinal function are required to induce intestinal insufficiency in mice.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Understanding the gut microbiota to shape the future of intestinal failure care: a systematic review of the evidence.European journal of pediatrics · 2026Pooled it
- Multi-kingdom gut microbiota analyses identify biomarkers of different types of pediatric short bowel syndrome.mSystems · 2026Article
- Laparoscopic endostapler partial cecal resection in complicated appendicitis with appendiceal base involvement: a single-center retrospective study.BMC surgery · 2026Article
- Pre-, Pro-, Post- and Synbiotics in Pediatric Short Bowel Syndrome: A Narrative Review of Current Evidence.Children (Basel, Switzerland) · 2026Review
- Potential biomarkers for early periodontal inflammation: investigating CD5Scientific reports · 2026Article
- Perioperative anti-α4β7 Integrin Blockade Alters Wound Cell Infiltrate but Not the Functional Outcome of Ileocecal Anastomoses in Mice With Crohn's-like Ileitis.Inflammatory bowel diseases · 2025Article
- Differential effects of high-fat diet on salivary and gut microbiota.Frontiers in cellular and infection microbiology · 2025Article
- Changes in HLA-B27 Transgenic Rat Fecal Microbiota Following Tofacitinib Treatment and Ileocecal Resection Surgery: Implications for Crohn's Disease Management.International journal of molecular sciences · 2024Article
- Article
- Ileocolonic Healing after Small Ileocecal Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing by Local Mechanisms.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive bowel resection can lead to short bowel syndrome and intestinal failure. Resection-induced dysbiosis may be related to the specific anatomic site of resection and influences the disease progression. Although patients with end-jejunostomy are at high risk for intestinal failure, preservation of the ileocecal valve and colon counteracts this risk. The present study investigated the role of the cecum in maintaining microbial homeostasis after different types of small bowel resection. Male C57BL6/J mice were anesthetized by intraperitoneal injection of ketamine-xylazine and received extended ileocecal resection (extended ICR), limited ileocecal resection (limited ICR), or mid-small bowel resection (SBR). Stool samples were collected before surgery and between
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.