Evidence map›Paper›PMID 36346050›Full record

Trial reportJournal of the American Heart Association2022

Final 5-Year Report of the Randomized BIO-RESORT Trial Comparing 3 Contemporary Drug-Eluting Stents in All-Comers.

Eline H Ploumen, Tineke H Pinxterhuis, Rosaly A Buiten, Paolo Zocca, Peter W Danse, Carl E Schotborgh, Martijn Scholte, R Melvyn Tjon Joe Gin, Samer Somi, K Gert van Houwelingen and 8 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Long-Term (5-Years) Outcomes of Current Drug-Eluting Stents in Percutaneous Coronary Intervention: A Network Meta-Analysis of Randomized Controlled Trials.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Everolimus-eluting versus biolimus-eluting stents with biodegradable polymers in unselected patients undergoing percutaneous coronary intervention: five-year results of the randomised, non-inferiority SORT OUT VIII trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Trial
  8. Five-year outcomes of a drug-coated polymer-free biolimus-eluting stent versus an ultrathin-strut biodegradable-polymer sirolimus-eluting stent.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Trial
  9. Durable-polymer versus biodegradable-polymer drug-eluting stents in acute coronary syndromes: three-year outcomes of the HOST REDUCE POLYTECH RCT Trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Trial
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. The everolimus eluting Synergy MegatronCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Eline H PloumenDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0002-2689-3180
Tineke H PinxterhuisDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0002-9050-8742
Rosaly A BuitenDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.
Paolo ZoccaDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0003-2726-480X
Peter W DanseDepartment of Cardiology Rijnstate Hospital Arnhem The Netherlands.ORCID 0000-0002-6240-361X
Carl E SchotborghDepartment of Cardiology Haga Hospital The Hague The Netherlands.ORCID 0000-0001-7630-0868
Martijn ScholteDepartment of Cardiology Albert Schweitzer Hospital Dordrecht The Netherlands.ORCID 0000-0002-8146-3271
R Melvyn Tjon Joe GinDepartment of Cardiology Rijnstate Hospital Arnhem The Netherlands.ORCID 0000-0001-9980-548X
Samer SomiDepartment of Cardiology Haga Hospital The Hague The Netherlands.ORCID 0000-0002-0143-7197
K Gert van HouwelingenDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0003-0410-2138
Martin G StoelDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.
H A F de ManDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.
Marc HartmannDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.
Gerard C M LinssenDepartment of Cardiology Hospital Group Twente Almelo, Hengelo The Netherlands.ORCID 0000-0002-3339-1955
Liefke C van der HeijdenDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0002-7264-509X
Marlies M KokDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0003-0101-2217
Carine J M DoggenDepartment of Health Technology and Services Research, Faculty BMS Technical Medical Centre, University of Twente Enschede The Netherlands.ORCID 0000-0003-4766-4333
Clemens von BirgelenDepartment of Cardiology Thoraxcentrum Twente, Medisch Spectrum Twente Enschede The Netherlands.ORCID 0000-0002-5128-2832
Medisch Spectrum Twente · NLHaga Hospital · NLRijnstate Hospital · NLAlbert Schweitzer Ziekenhuis · NLUniversity of Twente · NLZiekenhuis Groep Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In a previous trial, higher 5-year mortality was observed following treatment with biodegradable polymer Orsiro sirolimus-eluting stents (SES). We assessed 5-year safety and efficacy of all-comers as well as patients with diabetes treated with SES or Synergy everolimus-eluting stents (EES) versus durable polymer Resolute Integrity zotarolimus-eluting stents (ZES). Methods and Results The randomized BIO-RESORT (Comparison of Biodegradable Polymer and Durable Polymer Drug-Eluting Stents in an All Comers Population) trial enrolled 3514 all-comer patients at 4 Dutch cardiac centers. Patients aged ≥18 years who required percutaneous coronary intervention were eligible. Participants were stratified for diabetes and randomized to treatment with SES, EES, or ZES (1:1:1). The main end point was target vessel failure (cardiac mortality, target vessel myocardial infarction, or target vessel revascularization). Five-year follow-up was available in 3183 of 3514 (90.6%) patients. The main end point target vessel failure occurred in 142 of 1169 (12.7%) patients treated with SES, 130 of 1172 (11.6%) treated with EES, versus 157 of 1173 (14.1%) treated with ZES (hazard ratio [HR], 0.89 [95% CI, 0.71-1.12],

Indexed as

Coronary Artery DiseaseDiabetes MellitusDrug-Eluting StentsPercutaneous Coronary InterventionAdolescentAdultEverolimusHumansPolymersProsthesis DesignSirolimusTreatment OutcomeEverolimusPolymersSirolimuszotarolimusbiodegradable polymerdrug‐eluting stentdurable polymerpercutaneous coronary interventionrandomized clinical trial

Identifiers

PMID36346050
PMCPMC9750072
OpenAlexW4308554058

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.