Evidence map›Paper›PMID 36346017›Full record

ArticleRenal failure2022

Dynamic changes of neutrophil-to-lymphocyte ratio in brain-dead donors and delayed graft function in kidney transplant recipients.

Yongfang Zhang, Rumin Liu, Xiaolin Zhao, Zhiyu Ou, Shengnan Wang, Dongmei Wang, Kaibin Huang, Suyue Pan, Yongming Wu

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. [Comment on the article "Elevated neutrophil-lymphocyte ratio and delayed graft function"].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yongfang ZhangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Rumin LiuDepartment of Kidney Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiaolin ZhaoDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhiyu OuDepartment of Kidney Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Shengnan WangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Dongmei WangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Kaibin HuangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Suyue PanDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yongming WuDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Southern Medical University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNeutrophil-to-lymphocyte ratio (NLR) is a simple parameter implying the inflammatory status. We aimed to explore the association of brain-dead donor NLR change with delayed graft function (DGF) in kidney transplant recipients.

methodsWe retrospectively analyzed the data on 102 adult brain-dead donors and their corresponding 199 kidney transplant recipients (2018 - 2021). We calculated ΔNLR by subtracting the NLR before evaluating brain death from the preoperative NLR. Increasing donor NLR was defined as ΔNLR > 0.

resultsForty-four (22%) recipients developed DGF after transplantation. Increasing donor NLR was significantly associated with the development of DGF in recipients (OR 2.8, 95% CI 1.2 - 6.6;

conclusionsDynamic changes of donor NLR are promising in predicting post-transplant DGF. It will assist clinicians in the early recognition and management of renal graft dysfunction. Validation of this new biomarker in a large study is needed.

Indexed as

Acute Kidney InjuryKidney TransplantationAdultBrainBrain DeathDelayed Graft FunctionGraft SurvivalHumansLymphocytesNeutrophilsRetrospective StudiesRisk FactorsTissue DonorsTransplant Recipientsacute kidney injurybrain-dead donordelayed graft functionkidney transplantationNeutrophil-to-lymphocyte ratio

Identifiers

PMID36346017
PMCPMC9648373
OpenAlexW4308585475

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.