Evidence map›Paper›PMID 36345836›Full record

ReviewAugmentative and alternative communication (Baltimore, Md. : 1985)2023

Review of methods for conducting speech research with minimally verbal individuals with autism spectrum disorder.

Karen V Chenausky, Marc Maffei, Helen Tager-Flusberg, Jordan R Green

Registry-linked trialAbstract readReview
In one paragraph

Review in Augmentative and alternative communication (Baltimore, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07472829 (Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07472829 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder

Typeobservational_patient_registrySponsorChildren's Hospital of Chongqing Medical UniversityRan2026 to 2027Enrolled120ConditionsSpeech, Autism Spectrum Disorder (ASD)ArmsApproaches to ASD social intervention
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Proportion and Profile of Autistic Children Not Acquiring Spoken Language Despite Receiving Evidence-Based Early Interventions.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karen V ChenauskyMGH Institute of Health Professions, Charlestown, MA, USA.ORCID 0000-0002-4294-9228
Marc MaffeiMGH Institute of Health Professions, Charlestown, MA, USA.
Helen Tager-FlusbergDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Jordan R GreenMGH Institute of Health Professions, Charlestown, MA, USA.ORCID 0000-0002-1464-1373

Funding

Predicting and Otimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum DisorderP50DC018006 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KASARI, CONNIE L., TAGER-FLUSBERG, HELEN · 2019 to 2023
$12.3M
Prolonging Functional Speech in Persons with Amyotrophic Lateral Sclerosis: A Real-Time Virtual Vocal TractK24DC016312 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI GREEN, JORDAN R · 2017 to 2021
$949k
Identifying and Treating Childhood Apraxia of Speech in Minimally Verbal Children with AutismR00DC017490 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI CHENAUSKY, KAREN V · 2022 to 2024
$845k
Identifying and Treating Childhood Apraxia of Speech in Minimally Verbal Children with AutismK99DC017490 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI CHENAUSKY, KAREN V · 2019 to 2021
$298k
NIDCD NIH HHS K24 DC016312NIDCD NIH HHS K99 DC017490NIDCD NIH HHS P50 DC018006NIDCD NIH HHS R00 DC017490
6 · The paper itself

Abstract

The purpose of this paper was to review best-practice methods of collecting and analyzing speech production data from minimally verbal autistic speakers. Data on speech production data in minimally verbal individuals are valuable for a variety of purposes, including phenotyping, clinical assessment, and treatment monitoring. Both perceptual ("by ear") and acoustic analyses of speech can reveal subtle improvements as a result of therapy that may not be apparent when correct/incorrect judgments are used. Key considerations for collecting and analyzing speech production data from this population are reviewed. The definition of "minimally verbal" that is chosen will vary depending on the specific hypotheses investigated, as will the stimuli to be collected and the task(s) used to elicit them. Perceptual judgments are ecologically valid but subject to known sources of bias; therefore, training and reliability procedures for perceptual analyses are addressed, including guidelines on how to select vocalizations for inclusion or exclusion. Factors to consider when recording and acoustically analyzing speech are also briefly discussed. In summary, the tasks, stimuli, training methods, analysis type(s), and level of detail that yield the most reliable data to answer the question should be selected. It is possible to obtain rich high-quality data even from speakers with very little speech output. This information is useful not only for research but also for clinical decision-making and progress monitoring.

Indexed as

Autism Spectrum DisorderCommunication Devices for People with DisabilitiesCommunication DisordersHumansReproducibility of ResultsSpeechAugmentative and alternative communicationautism spectrum disorderchildhood apraxia of speechminimally verbalmotor speech disordersspeech production

Identifiers

PMID36345836
PMCPMC10364318

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.