ArticleAngewandte Chemie (International ed. in English)2023
Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes.
Article in Angewandte Chemie (International ed. in English), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Recoverable Fluorination Accelerates Ring-Opening Copolymerisation and Enables Post-Polymerisation-Modification of Polyesters.Angewandte Chemie (International ed. in English) · 2025Article
- Hypervalent Iodine-Catalyzed Fluorination of Diene-Containing Compounds: A Computational Study.Molecules (Basel, Switzerland) · 2024Article
- A decade of lessons in the activation of ArILChemical science · 2024Review
- Oxidative fluorination with Selectfluor: A convenient procedure for preparing hypervalent iodine(V) fluorides.Beilstein journal of organic chemistry · 2024Article
- Article
- Photocatalytic redox-neutral selective single C(spChemical science · 2023Article
- Integrating I(I)/I(III) catalysis in reaction cascade design enables the synthesis of gem-difluorinated tetralins from cyclobutanols.Nature communications · 2023Article
- Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes.Angewandte Chemie (International ed. in English) · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A catalysis-based regioselective 1,4-fluorofunctionalization of trifluoromethyl substituted 1,3-dienes has been developed to access compact, highly functionalized products. The process allows E,Z-mixed dienes to be processed to a single E-alkene isomer, and leverages an inexpensive and operationally convenient I(I)/I(III) catalysis platform. The first example of catalytic 1,4-difluorination is disclosed and subsequently evolved to enable 1,4-hetero-difunctionalization, which allows δ-fluoro-alcohol and amine derivatives to be forged in a single operation. The protocol is compatible with a variety of nucleophiles including fluoride, nitriles, carboxylic acids, alcohols and even water thereby allowing highly functionalized products, with a stereocenter bearing both C(sp
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Registered trials
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