Evidence map›Paper›PMID 36345502›Full record

ReviewNeurobiology of sleep and circadian rhythms2022

Mood phenotypes in rodent models with circadian disturbances.

Kiyomichi Imamura, Toru Takumi

Abstract readReview
In one paragraph

Review in Neurobiology of sleep and circadian rhythms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kiyomichi ImamuraDepartment of Physiology and Cell Biology, Kobe University School of Medicine, Chuo, Kobe, 650-0017, Japan.
Toru TakumiDepartment of Physiology and Cell Biology, Kobe University School of Medicine, Chuo, Kobe, 650-0017, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many physiological functions with approximately 24-h rhythmicity (circadian rhythms) are generated by an internal time-measuring system of the circadian clock. While sleep/wake cycles, feeding patterns, and body temperature are the most widely known physiological functions under the regulation of the circadian clock, physiological regulation by the circadian clock extends to higher brain functions. Accumulating evidence suggests strong associations between the circadian clock and mood disorders such as depression, but the underlying mechanisms of the functional relationship between them are obscure. This review overviews rodent models with disrupted circadian rhythms on depression-related responses. The animal models with circadian disturbances (by clock gene mutations and artifactual interventions) will help understand the causal link between the circadian clock and depression.

Indexed as

CircadianClock geneCMS, chronic mild stressD1R-MSN, dopamine 1 receptor-expressing medium spiny neuronsDepressionDG, dentate gyrusDSPS, delayed sleep phase syndromeEMS, ethyl methane sulfonateFASPS, familial advanced sleep phase syndromeipRGCs, intrinsically photosensitive retinal ganglion cellsLAN, light-at-nightLHb, lateral habenulaMAOA, monoamine oxidase AMDD, major depressive disorderMood disorderNAc, nucleus accumbensPHb, perihabenular nucleusSCN, suprachiasmatic nucleusSleep disordervLGN/IGL, ventral lateral geniculate nucleus and intergeniculate leafletVTA, ventral tegmental area

Identifiers

PMID36345502
PMCPMC9636574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.