Conformational Trimorphism in an Ionic Cocrystal of Hesperetin.

Shasha Jin, Molly M Haskins, Yassin H Andaloussi, Ruiling Ouyang, Junbo Gong, Michael J Zaworotko

Open access · hybridAbstract read

In one paragraph

Article in Crystal growth & design, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

1.4field-weighted citation impact, top 18% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

Control of site-specific deprotonation through mechanochemical interconversion of two ionic cocrystal forms of resveratrol.Journal of materials chemistry. B · 2026
Article
Flavonoid-Based Cocrystals: A Comprehensive Study on Their Synthesis, Characterization, Physicochemical Properties and Applications.Molecules (Basel, Switzerland) · 2025
Review
Crystal engineering of ionic cocrystals comprising Na/K salts of hesperetin with hesperetin molecules and solubility modulation.IUCrJ · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shasha JinDepartment of Chemical Sciences, Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland.

Molly M HaskinsDepartment of Chemical Sciences, Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland.

Yassin H AndaloussiDepartment of Chemical Sciences, Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland.

Ruiling OuyangState Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China.

Junbo GongState Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China.ORCID https://orcid.org/0000-0002-3376-3296

Michael J ZaworotkoDepartment of Chemical Sciences, Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland.ORCID https://orcid.org/0000-0002-1360-540X

University of Limerick · IETianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the existence of conformational polymorphism in an ionic cocrystal (ICC) of the nutraceutical compound hesperetin (HES) in which its tetraethylammonium (TEA

Identifiers

PMID36345389

DOI10.1021/acs.cgd.2c00861

PMCPMC9634790

OpenAlexW4300982063

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.