Evidence map›Paper›PMID 36345237›Full record

ArticlePediatric pulmonology2023

Lung involvement in children with COVID-19 multisystem inflammatory syndrome.

Michele Ghezzi, Emma Longoni, Alice Munari, Irene Raso, Giacomo Biganzoli, Gianvincenzo Zuccotti, Enza D'Auria

Abstract readLetter
In one paragraph

Article in Pediatric pulmonology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Post-MIS-C cardiovascular outcomes: a systematic review.European journal of pediatrics · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michele GhezziAllergology and Pneumology Unit, V. Buzzi Children's Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-7434-9112
Emma LongoniDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, Italy.ORCID http://orcid.org/0000-0002-8293-3829
Alice MunariDepartment of Radiology, V. Buzzi Children's Hospital, Milano, Italy.
Irene RasoPediatric Cardiology Unit, "Vittore Buzzi" Children's Hospital, Milano, Italy.
Giacomo BiganzoliMedical Statistics Unit, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università degli Studi di Milano, Milan, Italy.
Gianvincenzo ZuccottiDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, Italy.
Enza D'AuriaAllergology and Pneumology Unit, V. Buzzi Children's Hospital, Milan, Italy.ORCID http://orcid.org/0000-0003-2750-5810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the COVID-19 pandemic, multisystem inflammatory syndrome in children (MIS-C) has been reported in increasing numbers, mostly focusing on cardiac dysfunction. Very few studies have evaluated lung involvement in terms of imaging findings, while data regarding pulmonary function in children with MIS-C are not available. The purpose of our study was to evaluate lung involvement in MIS-C by imaging and lung function by structured light plethysmography (SLP) at hospital admission and 6 months afterwards. Spirometry is the gold standard technique to evaluate lung function in children. However, SLP has the advantage of not requiring contact with the patient, offering an effective solution for the evaluation of lung function during the pandemic. To our knowledge this is the first study that aims to investigate pulmonary function by SLP in children with MIS-C.

Indexed as

COVID-19ChildHospitalizationHumansLungPandemicsSystemic Inflammatory Response SyndromechildrenCOVID19imaginginfections: pneumoniaMIS-Cpulmonary function testing (PFT)TBviral

Identifiers

PMID36345237
PMCPMC9877654

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.