Evidence map›Paper›PMID 36345053›Full record

ArticleGlobal spine journal2024

What Radiographic and Clinical Factors Ultimately Necessitate a C2-Sacrum Instrumented Posterior Spinal Fusion?

Justin Mathew, Scott L Zuckerman, Gerard Marciano, Matthew Simhon, Hannah Lin, Meghan Cerpa, Nathan J Lee, Venkat Boddapati, Ronald A Lehman, Zeeshan M Sardar and 3 more

Abstract read
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Justin MathewDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0002-7699-780X
Scott L ZuckermanDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Gerard MarcianoDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Matthew SimhonDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Hannah LinDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0003-0137-7515
Meghan CerpaDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Nathan J LeeDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0001-9572-5968
Venkat BoddapatiDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Ronald A LehmanDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Zeeshan M SardarDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Marc D DyrszkaDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Joseph M LombardiDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Lawrence G LenkeDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective

designSingle center, retrospective cohort.

methodsConsecutive C2-sacrum PSF patients operated on by 4 surgeons at a single-center from 2015-2020 were reviewed. Demographics, comorbidities, indications, surgical history, and radiographic parameters were collected.

results23 patients underwent C2-sacrum PSF. 13 (57%) were male, and 21 (91.3%) were adults. Mean age at time of first spine surgery was 44 years (range 5-71) and 53 years (range 14-72) at the time of C2-sacrum PSF. Six patients (26%) had osteoporosis, and 6 patients (26%) had neurologic comorbidities-including Parkinson's disease (4), cerebral palsy (1), and Brown Sequard syndrome (1). Four (17%) had connective tissue disease. Two patients underwent C2-sacrum PSF as an index procedure: (1) 67M with myelomatous fractures and 124° of cervicothoracic kyphosis; (2) 28F with severe Marfan syndrome with 140° thoracic scoliosis and 130° thoracic kyphosis. The remaining 21 (91%) underwent C2-sacrum PSF as a revision following prior spinal surgeries on average, 4 previous surgeries (range 1-13) over 10.5 years (range .3-37.4). Indications for the remaining 21 C2-sacrum PSF revision procedures included 17 (81%) for kyphosis (5 of whom also had significant coronal deformity), 1 (5%) for only coronal malalignment, 2 (10%) for instrumentation failure, and 1 (5%) for myelopathy.

conclusions91% (21/23) of patients requiring C2-sacrum PSF were treated as revisions of prior fusions, with a mean of 4 prior surgeries over 10 years. Over 80% of these patients underwent C2-sacrum PSF to address kyphosis. 26% had neurologic conditions, and 26% had osteoporosis.

Indexed as

C2 to sacrumkyphosisrevision surgerysacrumscoliosisspinal cord diseasespinal cord injuryspinal deformityspine surgery

Identifiers

PMID36345053
PMCPMC11289540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.