Evidence map›Paper›PMID 36344897›Full record

ArticleSurgical endoscopy2023

The impact of frailty on ventral hernia repair outcomes in a statewide database.

Quintin P Solano, Ryan Howard, Cody L Mullens, Anne P Ehlers, Lia D Delaney, Brian Fry, Mary Shen, Michael Englesbe, Justin Dimick, Dana Telem

Abstract read
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Impact of preoperative frailty status on decision regret following elective hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Minimally Invasive Surgery Benefits Frail Patients Undergoing Emergency Hernia Repairs.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Quintin P SolanoUniversity of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0002-5195-8601
Ryan HowardCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Cody L MullensCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Anne P EhlersCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Lia D DelaneyUniversity of Michigan Medical School, Ann Arbor, MI, USA.
Brian FryCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Mary ShenCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Michael EnglesbeCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Justin DimickCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.
Dana TelemCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA. dtelem@med.umich.edu.

Funding

NRSA Training CoreTL1TR002242 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLINSTAT, MICHAEL ALLAN · 2017 to 2021
$2.8M
Obesity Surgery Scientist Training ProgramT32DK108740 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Brigham Dimick, RANDY J SEELEY · 2016 to 2026
$2.2M
Developing and Implementing Evidence-Based Hernia CareK08HS025778 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TELEM, DANA ALEXA · 2018 to 2021
$561k
AHRQ HHS K08 HS025778NCATS NIH HHS TL1 TR002242NIDDK NIH HHS T32 DK108740NIH HHS TL1TR002242
6 · The paper itself

Abstract

introductionPreoperative frailty is a strong predictor of postoperative morbidity in the general surgery population. Despite this, there are a paucity of research examining the effect of frailty on outcomes after ventral hernia repair (VHR), one of the most common abdominal operations in the USA. We examined the association of frailty with short-term postoperative outcomes while accounting for differences in preoperative, operative, and hernia characteristics.

methodsWe retrospectively reviewed the Michigan Surgery Quality Collaborative Hernia Registry (MSQC-HR) for adult patients who underwent VHR between January 2020 and January 2022. Patient frailty was assessed using the validated 5-factor modified frailty index (mFI5) and categorized as follows: no (mFI5 = 0), moderate (mFI5 = 1), and severe frailty (mFI5 ≥ 2). Our primary outcome was any 30-day complication. Multivariable logistic regression was used to evaluate the association of frailty with outcomes while controlling for patient, operative, and hernia variables.

resultsA total of 4406 patients underwent VHR with a mean age (SD) of 55 (15) years, 2015 (46%) females, and 3591 (82%) white patients. The mean (SD) BMI of the cohort was 33 (8) kg/m2. A total of 2077 (47%) patients had no frailty, 1604 (36%) were moderately frail, and 725 (17%) were severely frail. The median hernia size (interquartile range) was 2.5 cm (1.5-4.0 cm). Severe frailty was associated with increased odds of any complication (adjusted Odds Ratio (aOR) 3.12, 95% CI 1.78-5.47), serious complication (aOR 5.25, 95% CI 2.17-13.19), SSI (aOR 3.41, 95% CI 1.58-7.34), and post-discharge adverse events (aOR 1.70, 95% CI 1.24-2.33).

conclusionAfter controlling for patient, operative, and hernia characteristics, frailty was independently associated with increased odds of postoperative complications. These findings highlight the importance of preoperative frailty assessment for risk stratification and to inform patient counseling.

Indexed as

FrailtyHernia, VentralAdultAftercareFemaleHumansMaleMiddle AgedPatient DischargePostoperative ComplicationsRetrospective StudiesRisk Factors

Identifiers

PMID36344897
PMCPMC9640794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.